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[壳聚糖对大肠杆菌培养物中T系列噬菌体增殖性感染的抑制作用]

[Inhibition by chitosan of productive infection of T-series bacteriophages in the Escherichia coli culture].

作者信息

Kochkina Z M, Pospeshny G, Chirkov S N

出版信息

Mikrobiologiia. 1995 Mar-Apr;64(2):211-5.

PMID:7616876
Abstract

The possibility of the use of chitosan aminopolysaccharide (poly-D-glucosamine) and its two salts--acetate and hydrochloride--to prevent phase infection of the Escherichia coli culture, strain B1, was studied. It was shown that chitosan inhibited productive infection caused by the bacteriophages T2 and T7, the efficiency of inhibition of both bacteriophages depending directly on the final concentration of chitosan in a medium. Neither chitosan nor its salts significantly prevented the growth of the bacterial culture.

摘要

研究了使用壳聚糖氨基多糖(聚-D-葡糖胺)及其两种盐——醋酸盐和盐酸盐——预防大肠杆菌B1菌株培养物的噬菌体感染的可能性。结果表明,壳聚糖可抑制由噬菌体T2和T7引起的增殖性感染,两种噬菌体的抑制效率直接取决于培养基中壳聚糖的终浓度。壳聚糖及其盐均未显著抑制细菌培养物的生长。

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