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支气管疫苗(Broncho-Vaxom)和WR-2721对造血及循环血细胞的联合辐射防护作用。

Combined radioprotective effect of Broncho-Vaxom and WR-2721 on hemopoiesis and circulating blood cells.

作者信息

Macková N O, Fedorocko P

机构信息

Department of Cellular and Molecular Biology, Faculty of Science, P.J. Safárik University, Kosice, Slovakia.

出版信息

Neoplasma. 1995;42(1):25-30.

PMID:7617070
Abstract

Possibilities of combined radioprotection, using preirradiation WR-2721 administration and post- or preirradiation Broncho-Vaxom administration in lethally whole-body gamma-irradiated mice were investigated. Combined modality treatments were more effective than individual treatments alone. The ameliorative influence of the combined radioprotection could be explained by the hemopoietic stem cell protection with WR-2721 and the stimulation by Broncho-Vaxom.

摘要

研究了在全身接受致死剂量γ射线照射的小鼠中,通过照射前给予WR-2721以及照射后或照射前给予支气管疫苗(Broncho-Vaxom)进行联合辐射防护的可能性。联合治疗方式比单独的个体治疗更有效。联合辐射防护的改善作用可以通过WR-2721对造血干细胞的保护以及支气管疫苗的刺激作用来解释。

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