Buckley J A, Scott W W, Siegelman S S, Kuhlman J E, Urban B A, Bluemke D A, Fishman E K
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Radiology. 1995 Aug;196(2):395-400. doi: 10.1148/radiology.196.2.7617851.
To compare spiral computed tomography (CT) with interscan spacing of 4-5 mm versus 8-10 mm for detection rate and level of confidence in diagnosis of pulmonary nodules.
Four radiologists (two junior and two senior faculty members) retrospectively reviewed 67 spiral CT studies with one to six nodules per study. Every second image was masked, which resulted in 8-mm sections every 8 or 10 mm; then all images reconstructed every 4 or 5 mm were reviewed. Lesions were classified as definite, probable, or possible.
Narrow interscan spacing yielded more lesions overall (583 vs 566, P < .025) and more definite lesions and fewer equivocal lesions (482 vs 431 and 101 vs 135, respectively; P < .055). The greatest effects were in the reduction of possible lesions (50 vs 88, P < .001) and in the reduction of false-positive diagnoses made by less experienced radiologists.
Increased reconstruction frequency of spiral CT volume data sets improves detection of pulmonary nodules and enhances confidence in the diagnosis.
比较层厚为4 - 5毫米与8 - 10毫米的螺旋计算机断层扫描（CT）对肺结节的检出率及诊断置信度。
四位放射科医生（两位初级和两位高级教员）回顾性分析了67项螺旋CT研究，每项研究中有1至6个结节。每隔一幅图像进行遮盖处理，从而形成每8或10毫米间隔的8毫米层厚图像；然后对所有重建的每4或5毫米层厚的图像进行分析。病变被分为确定、可能或疑似三类。
扫描层厚较窄时总体上发现的病变更多（583个对566个，P < .025），确定的病变更多，疑似病变更少（分别为482个对431个和101个对135个；P < .055）。最大的影响在于减少了疑似病变（50个对88个，P < .001）以及减少了经验较少的放射科医生做出的假阳性诊断。
增加螺旋CT容积数据集的重建频率可提高肺结节的检出率并增强诊断置信度。
