Agzamova R T, Zaslavskiĭ R M, Teĭblium M M, Perepelkin E G
Urol Nefrol (Mosk). 1995 May-Jun(3):29-30.
Circadian rhythms of hemocoagulations and platelet aggregation were determined in chronics with pyelonephritis suffering from or free of renal dysfunction. Chronostructure of relevant circadian rhythms was recorded before and after 3-week combined chronotherapy with heparin and curantil. The readings were taken 6 times a day. The results obtained at group-mean and individual cosinor analysis showed disorganization of circadian rhythms of hemostasis in the above patients. Combined heparin and curantil chronotherapy corrected the above defects. Normalization occurred on the treatment day 26.
在患有或未患肾功能不全的慢性肾盂肾炎患者中测定了血液凝固和血小板聚集的昼夜节律。在使用肝素和库兰特进行为期3周的联合时间疗法之前和之后，记录了相关昼夜节律的时间结构。每天进行6次读数。通过组均值和个体余弦分析获得的结果表明，上述患者的止血昼夜节律紊乱。肝素和库兰特联合时间疗法纠正了上述缺陷。在治疗第26天恢复正常。
