单纯氟西汀过量后发作。

Seizure after isolated fluoxetine overdose.

作者信息

Braitberg G, Curry S C

机构信息

Department of Medical Toxicology, Good Samaritan Regional Medical Center, Phoenix, Arizona, USA.

出版信息

Ann Emerg Med. 1995 Aug;26(2):234-7. doi: 10.1016/s0196-0644(95)70157-5.

DOI:10.1016/s0196-0644(95)70157-5

PMID:7618791

Abstract

Previous case reports of seizures following fluoxetine overdose have not adequately ruled out ingestion of other substances and have lacked documentation of increased serum drug levels. We present a case of seizure following fluoxetine overdose in a previously well patient with a clear history of sole ingestion. We ruled out the presence of other substances with comprehensive drug screening and documented increased serum levels of fluoxetine and its active metabolite.

摘要

先前关于氟西汀过量后癫痫发作的病例报告并未充分排除摄入其他物质的可能性，且缺乏血清药物水平升高的记录。我们报告一例先前健康的患者在明确有单独摄入氟西汀病史后出现癫痫发作的病例。我们通过全面的药物筛查排除了其他物质的存在，并记录了血清中氟西汀及其活性代谢物水平的升高。