Watanabe Y, Tanaka H, Tanizawa M
Department of Internal Medicine, Kamo Hospital.
Arerugi. 1995 May;44(5):529-33.
From April 1992 we introduced beclomethasone dipropionate (BDP) inhalation therapy with a large spacer for patients with bronchial asthma who were admitted to the internal medicine department of our hospital because of an exacerbation of asthma. To investigate the influence of this BDP inhalation therapy on emergency room visits by patients with bronchial asthma, we studied the patients who were admitted to the emergency room at our hospital with asthmatic attacks from April 1991 to March 1994. A significant (p < 0.05) reduction in the number of patients who visited our emergency room with asthmatic attacks was found over the 3 years: from April 1991 to March 1992 (before the introduction of BDP inhalation therapy), 575 patients (47.9 +/- 7.5 patients/month) were admitted with asthmatic attacks; from April 1992 to March 1993, 341 patients (28.4 +/- 13.0 patients/month) were admitted, and from April 1993 to March 1994, 285 patients (25.1 +/- 9.2 patients/month). Among the patients who were admitted to our emergency room, the proportion of first-visit patient tended to increase. We studied 27 emergency-room-visit patients who attended our hospital regularly from one year before to one year after the introduction of BDP therapy. The therapy failed to control asthmatic symptoms in 12 patients on long courses of oral corticosteroids, on the other hand control of 15 patients without oral steroid was favorable. These results suggests that BDP inhalation therapy with a large spacer decreases the number of emergency room visits by patients with bronchial asthma.
自1992年4月起,我们对因哮喘加重而入住我院内科的支气管哮喘患者采用大容积储雾罐进行丙酸倍氯米松(BDP)吸入治疗。为研究这种BDP吸入治疗对支气管哮喘患者急诊就诊的影响,我们对1991年4月至1994年3月期间因哮喘发作入住我院急诊室的患者进行了研究。在这3年中,因哮喘发作前来我院急诊室就诊的患者数量显著减少(p < 0.05):1991年4月至1992年3月(BDP吸入治疗引入前),有575例患者(47.9±7.5例/月)因哮喘发作入院;1992年4月至1993年3月,有341例患者(28.4±13.0例/月)入院;1993年4月至1994年3月,有285例患者(25.1±9.2例/月)入院。在入住我院急诊室的患者中,初诊患者的比例有上升趋势。我们研究了27例在BDP治疗引入前一年至引入后一年定期到我院就诊的急诊患者。在长期口服皮质类固醇的12例患者中,该治疗未能控制哮喘症状,而在未使用口服类固醇的15例患者中,哮喘得到了良好控制。这些结果表明,使用大容积储雾罐的BDP吸入治疗可减少支气管哮喘患者的急诊就诊次数。