Ben-Shlomo Y, Sieradzan K
Department of Community Health and General Practice, Trinity College, Dublin.
Br J Gen Pract. 1995 May;45(394):261-8.
Since the introduction of levodopa therapy for idiopathic Parkinson's disease over 20 years ago, there has been an awakening of research interest in this chronic neuro-degenerative disorder. This paper describes current understanding of the role of genetic and environmental factors in the aetiology of idiopathic Parkinson's disease and problems associated with both diagnosis and management. It briefly outlines both pharmacological and non-pharmacological options for treatment. Despite an increasing armoury of available treatments, the optimum management for this condition remains controversial.
自20多年前左旋多巴疗法被引入用于治疗特发性帕金森病以来，对这种慢性神经退行性疾病的研究兴趣开始复苏。本文阐述了目前对遗传和环境因素在特发性帕金森病病因学中的作用以及与诊断和管理相关问题的理解。它简要概述了治疗的药理学和非药理学选择。尽管可用的治疗方法越来越多，但针对这种疾病的最佳管理仍存在争议。
