Medansky R S, Handler R M, Cook W, Willoughby C B, Fellner M J
Int J Dermatol. 1979 Jan-Feb;18(1):83-8. doi: 10.1111/j.1365-4362.1979.tb01921.x.
The effectiveness and safety of fluocinonide 0.05% in a cream base (FAPG cream: fatty acid propylene glycol) were evaluated in 105 patients with recalcitrant corticosteroid-responsive dermatoses that had failed to respond adequately to at least two weeks' previous treatment with one of 21 other topical corticosteroid preparations. At the end of the three weeks, 66 (71.0%) of the 93 patients who qualified for analysis showed excellent to moderate improvement with fluocinonide. Side effects were rare and of a minor nature. The general effectiveness of fluocinonide is indicated in this single-blind trail in which excellent or moderate results predominated in 8 of the 12 different diagnosis.
对105例顽固性皮质类固醇反应性皮肤病患者进行了评估，这些患者对至少21种其他外用皮质类固醇制剂之一进行了至少两周的先前治疗后仍未充分反应。使用0.05%氟轻松乳膏基质（FAPG乳膏：脂肪酸丙二醇）。在三周结束时，93例符合分析条件的患者中有66例（71.0%）使用氟轻松后显示出优异至中度改善。副作用很少且性质轻微。在这项单盲试验中表明了氟轻松的总体有效性，在12种不同诊断中的8种中，结果优异或中度的情况占主导。
