Brink A J, van Straten A, van Rensburg A J
Department of Medical Microbiology, University of Pretoria, South Africa.
Clin Infect Dis. 1995 May;20(5):1327-32. doi: 10.1093/clinids/20.5.1327.
Shewanella (Pseudomonas) putrefaciens is a rare pathogen in humans, and to our knowledge only 13 cases of S. putrefaciens bacteremia have ever been reported in the literature. In this retrospective study we describe 28 cases of S. putrefaciens bacteremia: 16 in premature and 1-day-old neonates, 9 in adults, and 3 in children younger than 1 year of age. All the babies presented with respiratory distress and/or pneumonia. Six of the adults had associated traumatic lesions of the lower extremity, and of the eight patients who died of sepsis, six were neutropenic. Polymicrobial bacteremia was seen in 18 cases. Three syndromes of bacteremic infection with S. putrefaciens appear to exist: the first is associated with prematurity and congenital pneumonia; the second with ulceration of the lower extremities; and the third (which is more fulminant), with an underlying debility. The findings in these 28 cases confirm the fact that S. putrefaciens can invade the bloodstream; however, the presence of concurrent bacteremia makes it difficult to determine the pathogenic role of this organism in septicemia.
腐败希瓦氏菌（假单胞菌属）是一种人类罕见的病原体，据我们所知，文献中仅报道过13例腐败希瓦氏菌血症病例。在这项回顾性研究中，我们描述了28例腐败希瓦氏菌血症病例：16例为早产儿和1日龄新生儿，9例为成年人，3例为1岁以下儿童。所有婴儿均表现出呼吸窘迫和/或肺炎。6名成年人伴有下肢创伤性损伤，在8例死于败血症的患者中，6例为中性粒细胞减少症患者。18例病例中出现了多菌血症。似乎存在三种由腐败希瓦氏菌引起的菌血症感染综合征：第一种与早产和先天性肺炎有关；第二种与下肢溃疡有关；第三种（更暴发性）与潜在的身体虚弱有关。这28例病例的研究结果证实了腐败希瓦氏菌能够侵入血流这一事实；然而，并发菌血症的存在使得难以确定该生物体在败血症中的致病作用。
