重组人促红细胞生成素治疗合并肾衰竭的多发性骨髓瘤贫血
[Recombinant human erythropoietin in the treatment of the anemia of multiple myeloma with kidney failure].
作者信息
Arenas Gracia M, Abad Gosálvez A, Colomina Avilés J, Pascual Pérez R, Ferriz Moreno P
机构信息
Servicio de Medicina Interna, Hospital General de Area de Elda, Alicante.
出版信息
An Med Interna. 1995 Apr;12(4):187-8.
PMID:7620064
Abstract
A patient with advanced multiple myeloma (MM) and renal failure presented a severe chronic anemia requiring frequent blood transfusions. Treatment with recombinant human erythropoietin (rHuEPO) led to a rapid improvement of anemia, and further blood transfusions were not required. Pathophysiological studies about the erythropoiesis in patients with MM and trials with rHuEPO in myeloma-associated anemia are commented.
摘要
一名患有晚期多发性骨髓瘤（MM）和肾衰竭的患者出现严重慢性贫血，需要频繁输血。使用重组人促红细胞生成素（rHuEPO）治疗后贫血迅速改善，无需进一步输血。本文对MM患者红细胞生成的病理生理学研究以及rHuEPO治疗骨髓瘤相关性贫血的试验进行了评论。
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