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长效氟奋乃静所致的神经阻滞剂恶性综合征

Neuroleptic malignant syndrome due to depot fluphenazine.

作者信息

Grunhaus L, Sancovici S, Rimon R

出版信息

J Clin Psychiatry. 1979 Feb;40(2):99-100.

PMID:762037
Abstract

The parenteral long-acting phenothiazines are drugs frequently used in the treatment of hospitalized and ambulatory psychiatric patients. The usual side effects of these drugs are familiar to psychiatrists. However, the "Neuroleptic malignant syndrome" reported in this paper can give rise to considerable diagnostic difficulty. The clinical characteristics and differential diagnosis of this syndrome are described with a care report. The need for prompt initiation of adequate therapy is stressed.

摘要

胃肠外长效吩噻嗪类药物常用于治疗住院及非住院的精神科患者。精神科医生对这些药物的常见副作用很熟悉。然而,本文报道的“抗精神病药恶性综合征”可能会引起相当大的诊断困难。本文通过一份病例报告描述了该综合征的临床特征及鉴别诊断。强调了迅速开始适当治疗的必要性。

相似文献

1
Neuroleptic malignant syndrome due to depot fluphenazine.长效氟奋乃静所致的神经阻滞剂恶性综合征
J Clin Psychiatry. 1979 Feb;40(2):99-100.
2
Haloperidol decanoate as a replacement for maintenance therapy with intramuscular fluphenazine decanoate in schizophrenia and other chronic psychoses.癸酸氟哌啶醇替代癸酸氟奋乃静进行精神分裂症及其他慢性精神病的维持治疗。
Acta Psychiatr Belg. 1982 Mar-Apr;82(2):216-23.
3
Therapy with injectable fluphenazines.注射用氟奋乃静治疗
Curr Psychiatr Ther. 1976;16:177-89.
4
Tardive dyskinesia in outpatients on depot phenothiazine.接受长效吩噻嗪治疗的门诊患者的迟发性运动障碍
West Indian Med J. 1989 Dec;38(4):228-33.
5
Iatrogenic morbidity in patients taking depot fluphenazine.接受氟奋乃静长效注射剂治疗的患者的医源性发病率。
Am J Psychiatry. 1979 Jul;136(7):976-7. doi: 10.1176/ajp.136.7.976.
6
[Antiparkinson drugs in neuroleptic treatment: comparative study of progressive and abrupt withdrawal].
Encephale. 1995 May-Jun;21(3):209-15.
7
[Long-action neuroleptic agents (delayed-action neuroleptics)].
Rev Prat. 1972 Apr 21;22(12):1941-53.
8
Depot fluphenazine: risk/benefit ratio.氟奋乃静长效注射剂:风险/效益比。
J Clin Psychiatry. 1984 May;45(5 Pt 2):28-35.
9
[Results of the use of fluphenazine in a depot preparation].
Psychiatr Neurol Med Psychol Beih. 1975;20-21:176-82.
10
Discontinuation of oral and depot fluphenazine in schizophrenic patients after one year of continuous medication: a controlled study.精神分裂症患者连续服药一年后停用口服和长效氟奋乃静:一项对照研究。
Adv Biochem Psychopharmacol. 1980;24:483-93.

引用本文的文献

1
The management challenges of a case with Flupentixol-induced neuroleptic malignant syndrome.氟哌啶醇致神经阻滞剂恶性综合征病例的管理挑战。
Neuropsychopharmacol Rep. 2023 Mar;43(1):154-159. doi: 10.1002/npr2.12315. Epub 2022 Dec 30.
2
Neuroleptic malignant syndrome: a complication of neuroleptics and cocaine abuse.抗精神病药恶性综合征:抗精神病药与可卡因滥用的一种并发症。
Psychiatr Q. 1991 Winter;62(4):299-309. doi: 10.1007/BF01958798.