危及生命的脑型红斑狼疮的多模式治疗：脑脊液置换术的益处

Multimodal therapy in life-threatening cerebral lupus erythematosus: the benefit of cerebrospinal fluid pheresis.

作者信息

Pfausler B, Bösch S, Grubwieser G, Vollert H, Greil R, Hagn C, Schmutzhard E

机构信息

Department of Neurology, University of Innsbruck, Medical School, Austria.

出版信息

Int Arch Allergy Immunol. 1995 Aug;107(4):592-4. doi: 10.1159/000237105.

DOI:10.1159/000237105

PMID:7620374

Abstract

A 27-year-old female patient with severe cerebral systemic lupus erythematosus did not respond to conventional therapy, including high-dose corticosteroids and high-dose pulsed cyclophosphamide therapy. Cerebrospinal fluid filtration (pheresis) led to rapid and lasting neurological improvement and clinical cure.

摘要

一名27岁患有严重脑型系统性红斑狼疮的女性患者，对包括大剂量皮质类固醇和大剂量脉冲环磷酰胺治疗在内的常规治疗均无反应。脑脊液滤过（血液成分分离法）使神经功能迅速且持久地改善，并实现了临床治愈。