Reid T, Rubins J B, Levine J, DeCelles J, Silvis S
Department of Medicine, Veterans Affairs Medical Center, Minneapolis, USA.
Arch Fam Med. 1995 Aug;4(8):715-7. doi: 10.1001/archfami.4.8.715.
We report an unusual case of a primary colonic bezoar composed of extended-release formulations of nifedipine and procainamide. Although these bezoars are rare, the increasingly frequent application of extended-release delivery systems to other commonly prescribed medications may increase the incidence of such bezoars in vulnerable patients. Clinicians should be aware of this potential problem when prescribing these medications, and have a high index of suspicion when painful or refractory constipation occurs.
我们报告了一例罕见的原发性结肠粪石病例，其由硝苯地平缓释制剂和普鲁卡因胺组成。尽管这些粪石较为罕见，但缓释给药系统在其他常用处方药中的应用日益频繁，这可能会增加此类粪石在易患患者中的发生率。临床医生在开具这些药物处方时应意识到这一潜在问题，当出现疼痛性或难治性便秘时应高度怀疑。
