Lindblad B, Wakefield T W, Stanley T J, Bergqvist D, Nichol B J, Greenfield L J, Stanley J C, Bergentz S E
Department of Surgery, Lund University, Malmö General Hospital, Sweden.
Eur J Vasc Endovasc Surg. 1995 Apr;9(3):267-71. doi: 10.1016/s1078-5884(05)80129-7.
To define current practice regarding the use of pharmacological prophylaxis to prevent postoperative graft occlusion.
Prospective open questionnaire.
Questionnaires regarding this subject were sent to vascular surgeons throughout the world to analyse current practice.
651 questionnaires were returned with a response rate of 62% and form the basis for this report. Data from 100,334 vascular reconstructions were reported in this survey. Prophylaxis against postoperative graft occlusions was common. Treatment periods were usually greater than 1 year. Among carotid surgery patients, 82% received prophylaxis, consisting mainly of low-dose acetysalicylic acid (ASA). In Mid-Europe the use of oral anticoagulation was more common than in other regions (p < 0.001). Among aneurysm surgery patients, 38% received prophylaxis. For infrainguinal bypass, ASA in low dose was the most commonly used agent worldwide. However, oral anticoagulation was more frequent in Mid-Europe, in contrast to South America where the combination of ASA and dipyridamole was most common. Considerable geographical differences regarding patient selection, the frequency of specific procedures and operative techniques existed.
Important world-wide differences exist regarding prophylaxis for postoperative graft occlusion.
明确目前使用药物预防术后移植物闭塞的实践情况。
前瞻性开放式问卷调查。
向世界各地的血管外科医生发送关于该主题的问卷，以分析当前的实践情况。
共收回651份问卷，回复率为62%，构成了本报告的基础。本次调查共报告了100334例血管重建的数据。预防术后移植物闭塞很常见。治疗期通常超过1年。在颈动脉手术患者中，82%接受了预防措施，主要是低剂量乙酰水杨酸（ASA）。在中欧，口服抗凝剂的使用比其他地区更为普遍（p < 0.001）。在动脉瘤手术患者中，38%接受了预防措施。对于下肢旁路移植术，低剂量ASA是全球最常用的药物。然而，在中欧口服抗凝剂的使用更为频繁，而在南美洲，ASA与双嘧达莫联合使用最为常见。在患者选择、特定手术的频率和手术技术方面存在相当大的地域差异。
在预防术后移植物闭塞方面，世界各地存在重要差异。
