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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Brooks V L, Quesnell R R, Cumbee S R, Bishop V S

Department of Physiology, Oregon Health Sciences University, Portland 97201-3098, USA.

Clin Exp Pharmacol Physiol. 1995 Feb;22(2):152-6. doi: 10.1111/j.1440-1681.1995.tb01972.x.

Pregnancy-induced changes in acute blood pressure regulation are reviewed. 2. Pregnant animals are less able to maintain arterial pressure during haemorrhage than non-pregnant animals. 3. Baroreceptor reflex-mediated increases in heart rate, renal sympathetic activity, vasopressin, ACTH and cortisol are reduced during pregnancy. Therefore, one explanation for the subnormal ability of pregnant animals to regulate arterial pressure during haemorrhage is that the baroreceptor reflex is not as effective. 4. Chronic increases in oestrogen levels in non-pregnant rabbits do not reduce the gain of baroreflex control of renal sympathetic activity. This and other findings suggest that oestrogen alone does not mediate the blunted baroreflex activity observed during pregnancy.

本文综述了妊娠引起的急性血压调节变化。2. 与未孕动物相比，孕畜在出血期间维持动脉血压的能力较弱。3. 妊娠期间，压力感受器反射介导的心率、肾交感神经活动、血管加压素、促肾上腺皮质激素和皮质醇增加有所减少。因此，孕畜在出血期间调节动脉血压能力欠佳的一种解释是压力感受器反射效果不佳。4. 未孕兔体内雌激素水平长期升高并不会降低压力反射对肾交感神经活动的控制增益。这一发现以及其他研究结果表明，仅雌激素本身并不能介导妊娠期间观察到的压力反射活动减弱。

Brooks V L, Quesnell R R, Cumbee S R, Bishop V S

Department of Physiology, Oregon Health Sciences University, Portland 97201-3098, USA.

Clin Exp Pharmacol Physiol. 1995 Feb;22(2):152-6. doi: 10.1111/j.1440-1681.1995.tb01972.x.

Pregnancy-induced changes in acute blood pressure regulation are reviewed. 2. Pregnant animals are less able to maintain arterial pressure during haemorrhage than non-pregnant animals. 3. Baroreceptor reflex-mediated increases in heart rate, renal sympathetic activity, vasopressin, ACTH and cortisol are reduced during pregnancy. Therefore, one explanation for the subnormal ability of pregnant animals to regulate arterial pressure during haemorrhage is that the baroreceptor reflex is not as effective. 4. Chronic increases in oestrogen levels in non-pregnant rabbits do not reduce the gain of baroreflex control of renal sympathetic activity. This and other findings suggest that oestrogen alone does not mediate the blunted baroreflex activity observed during pregnancy.

本文综述了妊娠引起的急性血压调节变化。2. 与未孕动物相比，孕畜在出血期间维持动脉血压的能力较弱。3. 妊娠期间，压力感受器反射介导的心率、肾交感神经活动、血管加压素、促肾上腺皮质激素和皮质醇增加有所减少。因此，孕畜在出血期间调节动脉血压能力欠佳的一种解释是压力感受器反射效果不佳。4. 未孕兔体内雌激素水平长期升高并不会降低压力反射对肾交感神经活动的控制增益。这一发现以及其他研究结果表明，仅雌激素本身并不能介导妊娠期间观察到的压力反射活动减弱。