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在清醒兔中,压力反射的改变发生在妊娠后期。

Alterations in the baroreflex occur late in pregnancy in conscious rabbits.

作者信息

Quesnell R R, Brooks V L

机构信息

Department of Physiology, Oregon Health Sciences University, Portland 97201-3098, USA.

出版信息

Am J Obstet Gynecol. 1997 Mar;176(3):692-4. doi: 10.1016/s0002-9378(97)70571-4.

DOI:10.1016/s0002-9378(97)70571-4
PMID:9077630
Abstract

Experiments were performed in conscious rabbits to investigate when during pregnancy cardiac baroreceptor reflex gain decreases. A decrease in gain was first observed after 3 weeks of gestation (-34.1 +/- 4.9 to -15.7 +/- 3.1 beats/min/mm Hg, p < 0.05) and became more pronounced after 4 weeks (-30.2 +/- 4.7 to -8.6 +/- 2.9 beats/min/mm Hg, p < 0.05). These results indicate that the attenuation of baroreflex function does not become fully manifest until late in pregnancy.

摘要

在清醒兔身上进行实验,以研究妊娠期间心脏压力感受器反射增益何时降低。妊娠3周后首次观察到增益降低(从-34.1±4.9降至-15.7±3.1次/分钟/毫米汞柱,p<0.05),4周后变得更加明显(从-30.2±4.7降至-8.6±2.9次/分钟/毫米汞柱,p<0.05)。这些结果表明,压力反射功能的减弱直到妊娠后期才完全显现出来。

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