Byrdy F A, Caruso J A
University of Cincinnati, Department of Chemistry, Ohio 45221-0172, USA.
Environ Health Perspect. 1995 Feb;103 Suppl 1(Suppl 1):21-3. doi: 10.1289/ehp.95103s121.
The analysis of environmental and biological samples often requires detection at the parts per billion (ppb) level. Plasma source mass spectrometry has potential as a method for the analysis and speciation of trace elements. This is due to the technique's highly selective nature and excellent sensitivity. In comparison to atomic emission detection, detection limits are usually two to three orders of magnitude lower for plasma MS determinations. Interfacing HPLC with plasma MS provides a means of separation that is necessary for speciation. Speciation involves the determination and quantitation of the various chemical forms of a particular element. A host of HPLC-ICP-MS techniques may be used to obtain this information. This brief report will focus on the most recent work in this area, with emphasis on the work done in our laboratory.
对环境和生物样品的分析通常需要达到十亿分之一（ppb）水平的检测。等离子体源质谱作为一种痕量元素分析和形态分析方法具有潜力。这是由于该技术具有高度选择性和出色的灵敏度。与原子发射检测相比，等离子体质谱测定的检测限通常要低两到三个数量级。将高效液相色谱（HPLC）与等离子体质谱联用提供了形态分析所需的分离手段。形态分析涉及特定元素各种化学形态的测定和定量。可以使用多种HPLC-ICP-MS技术来获取此信息。本简要报告将重点关注该领域的最新工作，尤其强调我们实验室所做的工作。
