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1
S fimbriae of uropathogenic Escherichia coli bind to primary human renal proximal tubular epithelial cells but do not induce expression of intercellular adhesion molecule 1.尿路致病性大肠杆菌的S菌毛可与原代人肾近端小管上皮细胞结合，但不会诱导细胞间黏附分子1的表达。
Infect Immun. 1995 Aug;63(8):3235-8. doi: 10.1128/iai.63.8.3235-3238.1995.
2
Differential expression of interleukin-6, intracellular adhesion molecule 1, and major histocompatibility complex class II molecules in renal carcinoma cells stimulated with S fimbriae of uropathogenic Escherichia coli.尿路致病性大肠杆菌S菌毛刺激的肾癌细胞中白细胞介素-6、细胞间黏附分子1和主要组织相容性复合体II类分子的差异表达
Infect Immun. 1993 Jul;61(7):3060-3. doi: 10.1128/iai.61.7.3060-3063.1993.
3
Binding to and killing of human renal epithelial cells by hemolytic P-fimbriated E. coli.
Kidney Int. 1994 Oct;46(4):1083-91. doi: 10.1038/ki.1994.370.
4
[Fimbriae as virulence factors of uropathogenic strains of Escherichia coli].[菌毛作为致病性大肠杆菌尿路致病菌株的毒力因子]
Med Wieku Rozwoj. 2005 Oct-Dec;9(4):743-52.
5
Synergy between type 1 fimbriae expression and C3 opsonisation increases internalisation of E. coli by human tubular epithelial cells.1型菌毛表达与C3调理作用之间的协同作用增强了人肾小管上皮细胞对大肠杆菌的内化作用。
BMC Microbiol. 2009 Mar 31;9:64. doi: 10.1186/1471-2180-9-64.
6
Internalization of Escherichia coli into human renal tubular epithelial cells.大肠杆菌内化进入人肾小管上皮细胞。
J Infect Dis. 1988 Jul;158(1):221-3. doi: 10.1093/infdis/158.1.221.
7
[The role of fimbriae of Escherichia coli in urinary tract infections].[大肠杆菌菌毛在尿路感染中的作用]
Hinyokika Kiyo. 1991 Sep;37(9):953-6.
8
P-fimbriae trigger mucosal responses to Escherichia coli in the human urinary tract.P菌毛引发人体泌尿系统对大肠杆菌的黏膜反应。
Cell Microbiol. 2001 Apr;3(4):255-64. doi: 10.1046/j.1462-5822.2001.00111.x.
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Escherichia coli bind to urinary bladder epithelium through nonspecific sialic acid mediated adherence.
FEMS Immunol Med Microbiol. 2003 Oct 24;39(1):45-50. doi: 10.1016/S0928-8244(03)00185-8.
10
Glycolipid receptors of F1C fimbrial adhesin of uropathogenic Escherichia coli.尿路致病性大肠杆菌F1C菌毛黏附素的糖脂受体
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Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal .肠道和肠外基因组岛的致病因素
Front Microbiol. 2020 Sep 25;11:2065. doi: 10.3389/fmicb.2020.02065. eCollection 2020.
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Adaptation of Escherichia coli traversing from the faecal environment to the urinary tract.大肠杆菌从粪便环境转移至泌尿道过程中的适应性变化。
Int J Med Microbiol. 2016 Dec;306(8):595-603. doi: 10.1016/j.ijmm.2016.10.005. Epub 2016 Nov 4.
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Epigenetic Influence of Dam Methylation on Gene Expression and Attachment in Uropathogenic Escherichia coli.母源 DNA 甲基化对尿路致病性大肠杆菌基因表达和黏附的表观遗传学影响
Front Public Health. 2016 Jun 27;4:131. doi: 10.3389/fpubh.2016.00131. eCollection 2016.
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Virulence and Fitness Determinants of Uropathogenic Escherichia coli.尿路致病性大肠埃希菌的毒力和适应力决定因素。
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Fimbrial profiles predict virulence of uropathogenic Escherichia coli strains: contribution of ygi and yad fimbriae.菌毛图谱预测泌尿道致病性大肠杆菌菌株的毒力：ygi 和 yad 菌毛的作用。
Infect Immun. 2011 Dec;79(12):4753-63. doi: 10.1128/IAI.05621-11. Epub 2011 Sep 12.
7
Polarized expression of Tamm-Horsfall protein by renal tubular epithelial cells activates human granulocytes.肾小管上皮细胞对Tamm-Horsfall蛋白的极化表达激活人类粒细胞。
Infect Immun. 2002 May;70(5):2650-6. doi: 10.1128/IAI.70.5.2650-2656.2002.
8
Interleukin-8 secretion of cortical tubular epithelial cells is directed to the basolateral environment and is not enhanced by apical exposure to Escherichia coli.皮质肾小管上皮细胞白细胞介素-8的分泌定向至基底外侧环境，且顶端暴露于大肠杆菌不会增强其分泌。
Infect Immun. 2000 Jan;68(1):328-34. doi: 10.1128/IAI.68.1.328-334.2000.
9
Influence of cloned tRNA genes from a uropathogenic Escherichia coli strain on adherence to primary human renal tubular epithelial cells and nephropathogenicity in rats.一株尿路致病性大肠杆菌的克隆tRNA基因对其黏附原代人肾小管上皮细胞及大鼠致病性的影响。
Infect Immun. 1996 Dec;64(12):5390-4. doi: 10.1128/iai.64.12.5390-5394.1996.

本文引用的文献

1
Selective cytokine production by epithelial cells following exposure to Escherichia coli.上皮细胞暴露于大肠杆菌后产生的细胞因子选择性
Infect Immun. 1993 Feb;61(2):602-9. doi: 10.1128/iai.61.2.602-609.1993.
2
Immunopathological changes in human cerebral malaria.人类脑型疟疾的免疫病理变化。
Clin Neuropathol. 1993 May-Jun;12(3):142-6.
3
Cytomegalovirus directly enhances MHC class I and intercellular adhesion molecule-1 expression on cultured proximal tubular epithelial cells.巨细胞病毒可直接增强培养的近端肾小管上皮细胞上的MHC I类分子和细胞间黏附分子-1的表达。
Transplantation. 1993 Jun;55(6):1367-71. doi: 10.1097/00007890-199306000-00029.
4
Differential expression of interleukin-6, intracellular adhesion molecule 1, and major histocompatibility complex class II molecules in renal carcinoma cells stimulated with S fimbriae of uropathogenic Escherichia coli.尿路致病性大肠杆菌S菌毛刺激的肾癌细胞中白细胞介素-6、细胞间黏附分子1和主要组织相容性复合体II类分子的差异表达
Infect Immun. 1993 Jul;61(7):3060-3. doi: 10.1128/iai.61.7.3060-3063.1993.
5
Specificity of S fimbriae on recombinant Escherichia coli: preferential binding to gangliosides expressing NeuGc alpha (2-3)Gal and NeuAc alpha (2-8)NeuAc.重组大肠杆菌上S菌毛的特异性：优先结合表达NeuGcα(2-3)Gal和NeuAcα(2-8)NeuAc的神经节苷脂。
Infect Immun. 1993 May;61(5):2108-15. doi: 10.1128/iai.61.5.2108-2115.1993.
6
Reciprocal exchange of minor components of type 1 and F1C fimbriae results in hybrid organelles with changed receptor specificities.1型菌毛和F1C菌毛的次要成分相互交换，产生了具有改变的受体特异性的杂交细胞器。
J Bacteriol. 1994 Apr;176(8):2227-34. doi: 10.1128/jb.176.8.2227-2234.1994.
7
Coexpression of intercellular adhesion molecule-1 and class I major histocompatibility complex antigens on hepatocyte membrane in chronic viral hepatitis.慢性病毒性肝炎中肝细胞细胞膜上细胞间黏附分子-1与I类主要组织相容性复合体抗原的共表达
J Clin Pathol. 1993 Nov;46(11):1004-8. doi: 10.1136/jcp.46.11.1004.
8
Binding to and killing of human renal epithelial cells by hemolytic P-fimbriated E. coli.
Kidney Int. 1994 Oct;46(4):1083-91. doi: 10.1038/ki.1994.370.
9
Distribution of cell adhesion molecules (ICAM-1, VCAM-1, ELAM-1) in renal tissue during allograft rejection.同种异体移植排斥反应期间肾组织中细胞黏附分子（ICAM - 1、VCAM - 1、ELAM - 1）的分布
Transplantation. 1993 Mar;55(3):610-5. doi: 10.1097/00007890-199303000-00027.
10
Tissue culture of human kidney epithelial cells of proximal tubule origin.源自近端小管的人肾上皮细胞的组织培养。
Kidney Int. 1984 Feb;25(2):383-90. doi: 10.1038/ki.1984.28.

尿路致病性大肠杆菌的S菌毛可与原代人肾近端小管上皮细胞结合，但不会诱导细胞间黏附分子1的表达。

S fimbriae of uropathogenic Escherichia coli bind to primary human renal proximal tubular epithelial cells but do not induce expression of intercellular adhesion molecule 1.

作者信息

Kreft B, Placzek M, Doehn C, Hacker J, Schmidt G, Wasenauer G, Daha M R, van der Woude F J, Sack K

机构信息

Klinik für Innere Medizin, Medizinischen Universität zu Lübeck, Germany.

出版信息

Infect Immun. 1995 Aug;63(8):3235-8. doi: 10.1128/iai.63.8.3235-3238.1995.

DOI:10.1128/iai.63.8.3235-3238.1995
PMID:7622256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC173445/
Abstract

We have recently reported an increase of expression of the intercellular adhesion molecule 1 by renal carcinoma cells in response to S fimbriae of Escherichia coli. Now we demonstrate that E. coli expressing S and P fimbriae strongly binds to human proximal tubular epithelial cells. However, in primary and simian virus 40-transfected renal tubular epithelial cells S fimbriae do not enhance the expression of intercellular adhesion molecule 1.

摘要

我们最近报道，肾癌细胞对大肠杆菌S菌毛产生应答后，细胞间黏附分子1的表达增加。现在我们证明，表达S菌毛和P菌毛的大肠杆菌能强烈结合人近端肾小管上皮细胞。然而，在原代和经猿猴病毒40转染的肾小管上皮细胞中，S菌毛不会增强细胞间黏附分子1的表达。