尿路致病性大肠杆菌的S菌毛可与原代人肾近端小管上皮细胞结合，但不会诱导细胞间黏附分子1的表达。
S fimbriae of uropathogenic Escherichia coli bind to primary human renal proximal tubular epithelial cells but do not induce expression of intercellular adhesion molecule 1.
作者信息
Kreft B, Placzek M, Doehn C, Hacker J, Schmidt G, Wasenauer G, Daha M R, van der Woude F J, Sack K
机构信息
Klinik für Innere Medizin, Medizinischen Universität zu Lübeck, Germany.
出版信息
Infect Immun. 1995 Aug;63(8):3235-8. doi: 10.1128/iai.63.8.3235-3238.1995.
Abstract
We have recently reported an increase of expression of the intercellular adhesion molecule 1 by renal carcinoma cells in response to S fimbriae of Escherichia coli. Now we demonstrate that E. coli expressing S and P fimbriae strongly binds to human proximal tubular epithelial cells. However, in primary and simian virus 40-transfected renal tubular epithelial cells S fimbriae do not enhance the expression of intercellular adhesion molecule 1.
摘要
我们最近报道，肾癌细胞对大肠杆菌S菌毛产生应答后，细胞间黏附分子1的表达增加。现在我们证明，表达S菌毛和P菌毛的大肠杆菌能强烈结合人近端肾小管上皮细胞。然而，在原代和经猿猴病毒40转染的肾小管上皮细胞中，S菌毛不会增强细胞间黏附分子1的表达。
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本文引用的文献
1
Selective cytokine production by epithelial cells following exposure to Escherichia coli.上皮细胞暴露于大肠杆菌后产生的细胞因子选择性
Infect Immun. 1993 Feb;61(2):602-9. doi: 10.1128/iai.61.2.602-609.1993.
2
Immunopathological changes in human cerebral malaria.人类脑型疟疾的免疫病理变化。
Clin Neuropathol. 1993 May-Jun;12(3):142-6.
3
Cytomegalovirus directly enhances MHC class I and intercellular adhesion molecule-1 expression on cultured proximal tubular epithelial cells.巨细胞病毒可直接增强培养的近端肾小管上皮细胞上的MHC I类分子和细胞间黏附分子-1的表达。
Transplantation. 1993 Jun;55(6):1367-71. doi: 10.1097/00007890-199306000-00029.
4
Differential expression of interleukin-6, intracellular adhesion molecule 1, and major histocompatibility complex class II molecules in renal carcinoma cells stimulated with S fimbriae of uropathogenic Escherichia coli.尿路致病性大肠杆菌S菌毛刺激的肾癌细胞中白细胞介素-6、细胞间黏附分子1和主要组织相容性复合体II类分子的差异表达
Infect Immun. 1993 Jul;61(7):3060-3. doi: 10.1128/iai.61.7.3060-3063.1993.
5
Specificity of S fimbriae on recombinant Escherichia coli: preferential binding to gangliosides expressing NeuGc alpha (2-3)Gal and NeuAc alpha (2-8)NeuAc.重组大肠杆菌上S菌毛的特异性：优先结合表达NeuGcα(2-3)Gal和NeuAcα(2-8)NeuAc的神经节苷脂。
Infect Immun. 1993 May;61(5):2108-15. doi: 10.1128/iai.61.5.2108-2115.1993.
6
Reciprocal exchange of minor components of type 1 and F1C fimbriae results in hybrid organelles with changed receptor specificities.1型菌毛和F1C菌毛的次要成分相互交换，产生了具有改变的受体特异性的杂交细胞器。
J Bacteriol. 1994 Apr;176(8):2227-34. doi: 10.1128/jb.176.8.2227-2234.1994.
7
Coexpression of intercellular adhesion molecule-1 and class I major histocompatibility complex antigens on hepatocyte membrane in chronic viral hepatitis.慢性病毒性肝炎中肝细胞细胞膜上细胞间黏附分子-1与I类主要组织相容性复合体抗原的共表达
J Clin Pathol. 1993 Nov;46(11):1004-8. doi: 10.1136/jcp.46.11.1004.
8
Binding to and killing of human renal epithelial cells by hemolytic P-fimbriated E. coli.
Kidney Int. 1994 Oct;46(4):1083-91. doi: 10.1038/ki.1994.370.
9
Distribution of cell adhesion molecules (ICAM-1, VCAM-1, ELAM-1) in renal tissue during allograft rejection.同种异体移植排斥反应期间肾组织中细胞黏附分子（ICAM - 1、VCAM - 1、ELAM - 1）的分布
Transplantation. 1993 Mar;55(3):610-5. doi: 10.1097/00007890-199303000-00027.
10
Tissue culture of human kidney epithelial cells of proximal tubule origin.源自近端小管的人肾上皮细胞的组织培养。
Kidney Int. 1984 Feb;25(2):383-90. doi: 10.1038/ki.1984.28.
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