一株尿路致病性大肠杆菌的克隆tRNA基因对其黏附原代人肾小管上皮细胞及大鼠致病性的影响。
Influence of cloned tRNA genes from a uropathogenic Escherichia coli strain on adherence to primary human renal tubular epithelial cells and nephropathogenicity in rats.
作者信息
Susa M, Kreft B, Wasenauer G, Ritter A, Hacker J, Marre R
机构信息
Klinikum, Abteilung für Medizinische Mikrobiologie und Hygiene der Universität Ulm, Germany.
出版信息
Infect Immun. 1996 Dec;64(12):5390-4. doi: 10.1128/iai.64.12.5390-5394.1996.
Abstract
The uropathogenic Escherichia coli strain 536 (O6:K15:H31) possesses pathogenicity islands which are incorporated into two tRNA genes, the selC and the leuX gene. The leuX gene influences the expression of different putative virulence factors. We demonstrate an effect of the leuX-specific tRNA on adherence and uropathogenicity.
摘要
尿路致病性大肠杆菌菌株536（O6:K15:H31）拥有致病岛，这些致病岛整合到两个tRNA基因，即selC基因和leuX基因中。leuX基因影响不同假定毒力因子的表达。我们证明了leuX特异性tRNA对黏附和尿路致病性的影响。
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本文引用的文献
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