Camacho M, Agnew A
Wellcome Research Centre for Parasitic Infections, Department of Biology, Imperial College of Science, Technology and Medicine, London, United Kingdom.
J Parasitol. 1995 Aug;81(4):637-40.
A simple flow culture apparatus was designed for the short-term in vitro culture of adult schistosomes. The use of this system allowed sensitive estimation of relative rates of glucose uptake by different species of schistosome. These data suggest that in parasites maintained carefully in conditions within the physiological range of glucose concentration, uptake of glucose is entirely carrier mediated. The rates of glucose uptake by Schistosoma haematobium and its close relative Schistosoma bovis were more than twice that recorded for Schistosoma mansoni. The relationship between reproductive output, glucose requirements, and susceptibility to immune attrition as adults is considered.
设计了一种简单的流动培养装置，用于成虫血吸虫的短期体外培养。该系统的使用能够灵敏地估计不同种类血吸虫对葡萄糖的摄取相对速率。这些数据表明，在葡萄糖浓度处于生理范围内的条件下精心培养的寄生虫中，葡萄糖摄取完全由载体介导。埃及血吸虫及其近亲牛血吸虫对葡萄糖的摄取速率是曼氏血吸虫的两倍多。文中还探讨了成虫的生殖产出、葡萄糖需求与免疫损耗易感性之间的关系。
