D'Erasmo M, Castiglione E, Del Vecchio A
Cattedra di Patologia Speciale Odontostomatologica, Università degli Studi di Roma La Sapienza, Roma.
Minerva Stomatol. 1995 Mar;44(3):81-7.
The authors discuss the indications for fibrin glue utilization in the sclerosing treatment of angiomas, with particular reference to cavernous and venous angiomas. The sclerosing agent may be employed in connection with embolization and subsequent surgery. The authors have successfully used the interstitial sclerosing technique to obtain the sclerosis of the thin threads of fibrous tissue stroma between blood vessels. The sclerosing therapy may cause the complete regression of "low flow" angiomas or, at least, a partial reduction that simplifies the ensuing surgical excision. In the case of partial regression of the angiomas obtained with the sclerosing therapy, the surgery of the remaining angioma causes a lower degree of bleeding; an increased reliability in the radicality of the intervention (due also to the reduced size of the lesion); and better results from an aesthetic-functional point of view.
作者讨论了纤维蛋白胶在血管瘤硬化治疗中的应用指征，尤其涉及海绵状血管瘤和静脉性血管瘤。硬化剂可与栓塞及后续手术联合使用。作者已成功运用间质硬化技术使血管间纤维组织基质的细丝发生硬化。硬化治疗可使“低流量”血管瘤完全消退，或至少部分缩小，从而简化后续手术切除。在通过硬化治疗使血管瘤部分消退的情况下，剩余血管瘤的手术导致的出血程度较低；手术根治性的可靠性增加（这也归因于病变尺寸减小）；从美学功能角度来看效果更好。
