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[氨基半乳糖葡糖醛聚糖在骨关节炎治疗中的镇痛作用]

[The analgesic effect of galactosaminoglycuronoglycan in the treatment of osteoarthrosis].

作者信息

Consoli G, Di Matteo L, Barlafante G, Agostinone A, Fratelli V

机构信息

Istituto di Reumatologia, Università degli Studi G. D'Annunzio, Pescara.

出版信息

Minerva Med. 1995 Apr;86(4):171-4.

PMID:7623974
Abstract

The analgesic effect of galactosamineglucuronoglycan sulfate (GGG) was evaluated in a series of patients with moderate to severe coxarthrosis and gonarthrosis. GGG was used at the daily dose of 800 mg, in conjunction with indomethacin, for a period of 6 months. In compliance with this controlled study the results obtained were compared with those observed in another group of patients with similar pathologies who were treated with indomethacin alone. Statistical elaboration of the values "between times" and "between treatments" showed that the combined treatment led to significantly better results; tolerance was good and compliance by the patients satisfactory.

摘要

对一系列中重度髋关节炎和膝关节炎患者评估了硫酸半乳糖胺葡糖醛酸聚糖(GGG)的镇痛效果。GGG的日剂量为800mg,与吲哚美辛联合使用,为期6个月。根据这项对照研究,将所得结果与另一组患有类似病症且仅用吲哚美辛治疗的患者所观察到的结果进行比较。对“不同时间”和“不同治疗方法”数值的统计学处理表明,联合治疗产生了明显更好的效果;耐受性良好,患者的依从性令人满意。

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