[Evaluation of treatment efficacy in gastritis and duodenitis in children with Helicobacter pylori infection].

The efficacy of Ventrisol treatment in gastritis and duodenitis in children infected with Helicobacter pylori was evaluated. Eighty-six children aged 3 to 18 years with chronic abdominal pain were examined. All children underwent gastrofiberoscopic examination. H. pylori infection was diagnosed on the bases of two of three diagnostic tests (urease, bacteriological, histological). H. pylori was detected in 50 children (56.4%). After a 4 week course of Ventrisol treatment, H. pylori eradication was obtained in 41 children (82%). Twenty-one children (42%) were completely cured, whereas in 20 children (40%) elimination of HP was observed although macroscopic and histological inflammatory changes were still present. The drug was well tolerated by 92.5% of children and its accumulation was not observed.