Herrington A M, Clifton G D
Department of Pharmacy, University of Kentucky Medical Center, Lexington 40536, USA.
Pharmacotherapy. 1995 Mar-Apr;15(2):182-200.
We reviewed the current literature on the toxicology and management of acute drug ingestions in adults after a MEDLINE search of English-language journal articles. Information on toxicology was also acquired from relevant textbooks. Present statistics were gathered through information from the U.S. Department of Health and Human Services and the American Association of Poison Control Centers. All patients with acute drug ingestions should be treated with supportive care initially, and when stabilized, undergo active removal of the ingested substance, based on the diagnostic and prognostic assessment. Identification of the ingested substance may prove useful in some instances when specific therapy or antidotes are indicated.
我们在对英文期刊文章进行MEDLINE检索后，回顾了有关成人急性药物摄入的毒理学及处理的当前文献。毒理学信息也从相关教科书中获取。现有统计数据通过美国卫生与公众服务部及美国中毒控制中心协会的信息收集而来。所有急性药物摄入患者最初都应接受支持性治疗，病情稳定后，根据诊断和预后评估，对摄入的物质进行积极清除。在某些需要特定治疗或解毒剂的情况下，确定摄入的物质可能会有所帮助。
