Karlsson R, Jonsson M, Edlund K, Evander M, Gustavsson A, Bodén E, Rylander E, Wadell G
Department of Family Medicine, University of Umeå, Sweden.
Sex Transm Dis. 1995 Mar-Apr;22(2):119-27. doi: 10.1097/00007435-199503000-00008.
Previous studies of relationships between genital human papillomavirus infection and tentative risk factors have yielded conflicting results, possibly because of inaccuracy of the viral detection methods used and differences in selection criteria.
To determine human papillomavirus prevalence and identify risk factors in a group of young Swedish women.
This was a population-based study involving completion of a structured questionnaire, analysis of cervical scrapings for human papillomavirus and Chlamydia trachomatis, and serologic tests for C. trachomatis and herpes simplex virus antibodies.
The prevalence of human papillomavirus infection was 22% among the sexually active women and 4% among the virgins. A number of factors were associated with human papillomavirus prevalence in univariate analysis, but logistic regression analysis showed that lifetime number of male sexual partners was the only independent risk factor for human papillomavirus infection (adjusted odds ratio, 7.45; 95% CI, 2.79-19.92 for six or more partners vs. one partner).
Human papillomavirus infection is a prevalent sexually transmitted disease among young Swedish women, and the lifetime number of male sexual partners is a major risk factor.
既往关于生殖器人乳头瘤病毒感染与暂定风险因素之间关系的研究结果相互矛盾，这可能是由于所用病毒检测方法的不准确以及选择标准的差异所致。
确定一组瑞典年轻女性中人乳头瘤病毒的流行情况并识别风险因素。
这是一项基于人群的研究，包括完成一份结构化问卷、分析宫颈刮片以检测人乳头瘤病毒和沙眼衣原体，以及进行沙眼衣原体和单纯疱疹病毒抗体的血清学检测。
在性活跃女性中人乳头瘤病毒感染率为22%，在处女中为4%。在单因素分析中，许多因素与人乳头瘤病毒流行率相关，但逻辑回归分析显示，男性性伴侣的终身数量是人乳头瘤病毒感染的唯一独立风险因素（与1名伴侣相比，6名或更多伴侣的调整优势比为7.45；95%可信区间为2.79 - 19.92）。
人乳头瘤病毒感染是瑞典年轻女性中一种普遍的性传播疾病，男性性伴侣的终身数量是一个主要风险因素。
