Lane A, Byrne M, Mulvany F, Kinsella A, Waddington J L, Walsh D, Larkin C, O'Callaghan E
St. John of God Psychiatric Service, Co. Dublin, Ireland.
Acta Psychiatr Scand. 1995 Apr;91(4):222-8. doi: 10.1111/j.1600-0447.1995.tb09772.x.
Using case register data, the overall marital rate among 5158 patients with mental illness was found to be comparable to the general population. The proportion of those ever married was markedly reduced in the schizophrenic group relative to those with a manic or neurotic illness. Men with schizophrenia had a particularly low rate of marriage. The overall marital fertility of the 3 groups was comparable to each other and appeared to be higher than that in the general population. In the schizophrenic group only, married men, particularly those with a family history of mental disorder, produced more children than married women. Men might represent a more fertile group of schizophrenic patients with some biological advantage of increased fecundity, which may help to compensate for negative selection pressures.
利用病例登记数据发现,5158名精神病患者的总体结婚率与普通人群相当。与患有躁狂症或神经症的患者相比,精神分裂症组中曾经结婚的人的比例明显降低。患有精神分裂症的男性结婚率尤其低。这三组的总体婚姻生育率彼此相当,且似乎高于普通人群。仅在精神分裂症组中,已婚男性,尤其是那些有精神障碍家族史的男性,生育的子女比已婚女性更多。男性可能代表了一组生育能力更强的精神分裂症患者,具有生育能力增强的某种生物学优势,这可能有助于抵消负面选择压力。