Fañanás L, Bertranpetit J
Laboratori d'Antropologia, Facultat de Biologia, Universitat de Barcelona, Spain.
Acta Psychiatr Scand. 1995 Mar;91(3):202-4. doi: 10.1111/j.1600-0447.1995.tb09767.x.
Data about the fertility of 142 schizophrenic patients and their ancestors are reported and compared with healthy people in a case-control study. The biological fitness of the patients is 76% of controls in individuals with at least one child, and 48% of controls in all patients, with clear low fertility rates in patients, especially in men. When looking at the previous generations, the existence of a significant increase in fertility in the relatives of schizophrenics was reinforced in the maternal lineage. These results confirm the previous findings about the decreasing fertility in schizophrenic patients and may be of interest in understanding the maintenance of the illness despite its genetic background.
在一项病例对照研究中，报告了142名精神分裂症患者及其祖先的生育能力数据，并与健康人进行了比较。在至少有一个孩子的个体中，患者的生物适应性是对照组的76%，在所有患者中是对照组的48%，患者的生育率明显较低，尤其是男性。当观察前几代人时，精神分裂症患者亲属的生育率显著增加在母系血统中更为明显。这些结果证实了之前关于精神分裂症患者生育率下降的研究发现，可能有助于理解尽管有遗传背景，但该疾病仍持续存在的原因。
