Patel J J, Munclinger M J, Mitha A S, Patel N
Department of Cardiology, University of Natal/Wentworth Hopsital, Durban, South Africa.
Br Heart J. 1995 Jun;73(6):555-8. doi: 10.1136/hrt.73.6.555.
To assess the outcome of percutaneous balloon dilatation of the mitral valve in critically ill young patients with intractable heart failure.
Retrospective analysis of all such patients presenting over a period of 4 years.
Of 432 consecutive patients undergoing percutaneous balloon dilatation of the mitral valve, 12 (mean age 29 years) with intractable heart failure were identified. Nine had severe pulmonary oedema and three had pulmonary oedema with severe right heart failure and hypotension. Three patients were pregnant and three required mechanical; ventilatory support.
Percutaneous balloon dilatation of the mitral valve was performed using the Inoue balloon technique. The procedure was shortened by excluding full right study, cardiac output measurement, and left ventriculography. The mitral valve morphology and mitral valve area were determined before and after percutaneous balloon dilatation using cross sectional Doppler echocardiography.
The procedure was technically successful in all patients. The mean (SD) echocardiographic value of the mitral valve area increased from 0.7 (0.1) to 1.4 (0.2) cm2 with a concomitant reduction in pulmonary artery systolic pressure (Doppler) from 81 (17) to 50 (7) mm Hg. There was a significant clinical improvement in all patients. The mean (range) fluoroscopy time for the procedure was 6.9 (1.7-14.1) min. During follow up (mean 10 months) nine patients were in New York Heart Association (NYHA) functional class I, one was in class II, one under NYHA elective mitral valve replacement, and one, who refused elective surgery, died suddenly at home.
Percutaneous balloon dilatation of the mitral valve can be performed as a life saving procedure in critically ill patients with mitral stenosis, as even a modest increase in valve area in these patients produces gratifying clinical improvement.
评估经皮二尖瓣球囊扩张术对患有顽固性心力衰竭的重症年轻患者的治疗效果。
对4年期间所有此类患者进行回顾性分析。
在连续432例行经皮二尖瓣球囊扩张术的患者中,确定有12例(平均年龄29岁)患有顽固性心力衰竭。9例有严重肺水肿,3例有肺水肿合并严重右心衰竭及低血压。3例患者为孕妇,3例需要机械通气支持。
采用Inoue球囊技术行经皮二尖瓣球囊扩张术。通过省略完整的右心检查、心输出量测量和左心室造影来缩短操作过程。使用横断面多普勒超声心动图在经皮二尖瓣球囊扩张术前和术后测定二尖瓣形态和二尖瓣面积。
所有患者手术在技术上均获成功。二尖瓣面积的平均(标准差)超声心动图值从0.7(0.1)cm²增加到1.4(0.2)cm²,同时肺动脉收缩压(多普勒)从81(17)mmHg降至50(7)mmHg。所有患者临床症状均有显著改善。该操作的平均(范围)透视时间为6.9(1.7 - 14.1)分钟。在随访期间(平均10个月),9例患者纽约心脏协会(NYHA)心功能分级为Ⅰ级,1例为Ⅱ级,1例接受NYHA择期二尖瓣置换术,1例拒绝择期手术,在家中突然死亡。
经皮二尖瓣球囊扩张术可作为二尖瓣狭窄重症患者的一种挽救生命的手术,因为即使这些患者的瓣膜面积有适度增加也会产生令人满意的临床改善。