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爱德华王子岛一家医院及两家慢性病护理机构的结核菌素皮肤试验

Tuberculin skin testing in a hospital and two chronic care facilities in Prince Edward Island.

作者信息

Langille D B, Sweet L E

出版信息

Can J Infect Control. 1995 Summer;10(2):41-4.

PMID:7626776
Abstract

OBJECTIVE

To determine the prevalence of initial and booster positive responses to tuberculin skin testing among staff of an acute care hospital, and among staff and residents of two chronic care facilities on Prince Edward Island (PEI).

PATIENTS AND METHODS

Two hundred and eighty-six staff from the hospital and the facilities, and 164 residents from the facilities were given tuberculin testing using 5 tuberculin units (TU) of purified protein derivative (PPD) of tuberculin. A two-step booster test was performed on 125 of 173 staff (73%) aged 35 years or older who initially tested negative, and on 138 of 141 residents (97.9%) at the chronic care homes.

RESULTS

The overall rate of initial tuberculin positivity among staff at the facilities was 15.7%. Among residents, the rate of positivity was 14.0%. Histories given by institutional staff of having previously received Bacille bilié de Calmette-Guérin vaccine (BCG) were associated with tuberculosis (TB) test reactivity, but not with mean reaction size. Staff with a history of BCG who tested positive did not differ in age from those testing negative. Institutional staff whose work involved patient contact were more likely to have a positive test than those whose work did not involve such contact. Booster positivity among those older than 35 years of age ranged from 2.0 to 5.2%.

CONCLUSIONS

These results suggest that, for health care institutions in PEI, tuberculin testing should be performed on all new or current hospital staff at risk of TB exposure, all new or current staff of chronic care facilities, and all new or current residents of chronic care facilities unless contraindicated. Booster testing should also be performed on all institutional staff and residents 35 years of age or older if their initial tuberculin test is negative.

摘要

目的

确定一家急症护理医院的工作人员以及爱德华王子岛(PEI)两家慢性病护理机构的工作人员和居民中结核菌素皮肤试验初次及加强阳性反应的患病率。

患者与方法

对来自医院和护理机构的286名工作人员以及护理机构的164名居民使用5结核菌素单位(TU)的结核菌素纯蛋白衍生物(PPD)进行结核菌素检测。对173名35岁及以上初次检测呈阴性的工作人员中的125名(73%)以及慢性病护理院141名居民中的138名(97.9%)进行了两步加强试验。

结果

护理机构工作人员中结核菌素初次阳性的总体发生率为15.7%。居民中的阳性率为14.0%。机构工作人员既往接种卡介苗(BCG)的病史与结核菌素试验反应性相关,但与平均反应大小无关。接种过BCG且检测呈阳性的工作人员与检测呈阴性的工作人员在年龄上无差异。工作涉及与患者接触的机构工作人员比工作不涉及此类接触的人员更有可能检测呈阳性。35岁以上人群的加强阳性率在2.0%至5.2%之间。

结论

这些结果表明,对于PEI的医疗机构,应对所有有接触结核病风险的新入职或在职医院工作人员、所有慢性病护理机构的新入职或在职工作人员以及所有慢性病护理机构的新入住或现住居民进行结核菌素检测,除非有禁忌证。如果初次结核菌素检测呈阴性,还应对所有35岁及以上的机构工作人员和居民进行加强检测。

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