Goldberg P K, Kozinn P J, Wise G J, Nouri N, Brooks R B
JAMA. 1979 Feb 9;241(6):582-4.
The 100,000 colony count has been used without careful evaluation for the diagnosis of renal candidiasis. Therefore, a prospective study was done on 1,004 urine samples from patients without signs of candidiasis to determine the incidence of candiduria and Candida colony counts. These were compared with colony counts from histologically proved cases of renal candidiasis. The incidence of candiduria varied from a low of 4% in men to a high of 39% in girls during their second week of antibiotic therapy. The overall mean colony count was 1,292 +/- 1,500. The mean colony count in clean-catch urine specimens from six proved cases of renal candidiasis was 23,750 +/- 12,311. The difference in colony counts from proved and unproved cases is statistically significant. Counts greater than 10,000 Candida organisms per milliliter require further investigation.
10万菌落计数在未经过仔细评估的情况下就被用于肾念珠菌病的诊断。因此，我们对1004份来自无念珠菌病体征患者的尿液样本进行了一项前瞻性研究，以确定念珠菌尿的发生率和念珠菌菌落计数。并将这些结果与经组织学证实的肾念珠菌病病例的菌落计数进行比较。在抗生素治疗的第二周，念珠菌尿的发生率从男性的4%低水平到女孩的39%高水平不等。总体平均菌落计数为1292±1500。6例经证实的肾念珠菌病病例的清洁中段尿标本中的平均菌落计数为23750±12311。经证实和未经证实病例的菌落计数差异具有统计学意义。每毫升念珠菌生物体计数大于10000需要进一步调查。
