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一种用于恒牙和乳牙化学机械去龋的改良试剂:一项体外研究。

An improved reagent for chemomechanical caries removal in permanent and deciduous teeth: an in vitro study.

作者信息

Yip H K, Stevenson A G, Beeley J A

机构信息

Department of Oral Sciences, University of Glasgow Dental Hospital and School, UK.

出版信息

J Dent. 1995 Aug;23(4):197-204. doi: 10.1016/0300-5712(95)91182-m.

Abstract

OBJECTIVES AND METHODS

An in vitro study has been carried out on the chemomechanical removal of caries in deciduous and permanent teeth. The aims of the study were to compare the efficacy of caries removal by various chemical agents including N-monochloro-DL-2-aminobutyrate (NMAB) and NMAB containing urea (NMAB-urea), to compare the efficacy on permanent and deciduous teeth and to study the dentinal surfaces produced.

RESULTS

The addition of urea to NMAB resulted in an improvement in the efficacy of caries removal. Sodium hypochlorite, saline and urea alone were also studied as caries removal agents, but were not significantly different from NMAB. Chemomechanical caries removal solutions were more effective in removing caries from deciduous teeth than from permanent teeth, especially in terms of the volume of solution used. The improvement on addition of urea was found to be greater in deciduous than in permanent teeth, the number of deciduous teeth with 'complete cares removal' being increased by about 25%. The dentinal surfaces of the cavities prepared using these solutions and in which 'complete caries removal' had been achieved were studied by scanning electron microscopy. Generally after treatment with NMAB or NMAB-urea, the surface appearance was very uneven with many undermined areas. NMAB-urea produced a 'cleaner' surface compared with that produced by NMAB alone.

CONCLUSIONS

NMAB appears to be potentially more effective and clinically more useful in removing caries in deciduous teeth than in permanent teeth, and the addition of urea may enhance its efficacy, especially in the treatment of paediatric dental patients.

摘要

目的与方法

针对乳牙和恒牙龋病的化学机械去除开展了一项体外研究。该研究的目的是比较包括N-一氯-DL-2-氨基丁酸酯(NMAB)和含尿素的NMAB(NMAB-尿素)在内的各种化学药剂去除龋病的效果,比较对恒牙和乳牙的效果,并研究产生的牙本质表面情况。

结果

向NMAB中添加尿素可提高龋病去除效果。还研究了单独使用次氯酸钠、生理盐水和尿素作为龋病去除剂的情况,但它们与NMAB没有显著差异。化学机械龋病去除溶液在去除乳牙龋病方面比恒牙更有效,尤其是在所用溶液体积方面。发现添加尿素后乳牙的改善比恒牙更大,“完全去除龋坏”的乳牙数量增加了约25%。使用这些溶液制备且已实现“完全去除龋病”的洞的牙本质表面通过扫描电子显微镜进行了研究。一般在用NMAB或NMAB-尿素处理后,表面外观非常不均匀,有许多 undermined区域。与单独使用NMAB产生的表面相比,NMAB-尿素产生的表面“更清洁”。

结论

NMAB在去除乳牙龋病方面似乎比恒牙更有效且在临床上更有用,添加尿素可能会增强其效果,特别是在儿科牙科患者的治疗中。

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