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灰黄霉素:梨形四膜虫的世代时间和三磷酸腺苷变化

Griseofulvin: generation time and ATP changes in the ciliate Tetrahymena pyriformis.

作者信息

Sparagano O A

机构信息

Ecotoxicology Research Group, A.M.S. School, University of Reading, UK.

出版信息

Life Sci. 1995;57(9):897-901. doi: 10.1016/0024-3205(95)02023-c.

Abstract

Tetrahymena pyriformis GL populations (20,000 cells/ml and 50,000 cells/ml) were studied at various times after exposure to griseofulvin. Growth rates were significantly different between controls and treated samples 90 min after treatment. ATP levels decreased in treated samples after 45 min. No differences were observed between controls and populations treated with acetone used to dissolve griseofulvin.

摘要

研究了梨形四膜虫GL群体(20,000个细胞/毫升和50,000个细胞/毫升)在接触灰黄霉素后的不同时间情况。处理后90分钟,对照样品和处理样品之间的生长速率存在显著差异。处理45分钟后,处理样品中的ATP水平下降。在对照样品和用溶解灰黄霉素的丙酮处理的群体之间未观察到差异。

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