Bernhardt H, Wellmer A, Zimmermann K, Knoke M
Klinik und Poliklinik für Innere Medizin, Ernst-Moritz-Arndt-Universität Greifswald, BR Deutschland.
Mycoses. 1995;38 Suppl 1:22-7. doi: 10.1111/j.1439-0507.1995.tb00480.x.
We used the model of fecal microflora under continuous flow culture (cfc) conditions to study the growth of Candida albicans in mixed cultures. The development of Candida is usually limited by the high germ counts of aerobic and anaerobic bacteria. Neither by the continuous inflow of C. albicans-cfc-monocultures nor by intermittent input of highly concentrated suspensions of C. albicans into the system a growth in fecal flora could be obtained. If the system was run under aerobic conditions a development of C. albicans with few hyphal growth could be observed. After some days however, the fecal flora again suppressed a further development of the yeasts. Only a marked destruction of the aerobic and anaerobic microflora by antibiotics resulted in a growth or overgrowth of Candida albicans.
我们使用连续流动培养（cfc）条件下的粪便微生物群落模型来研究白色念珠菌在混合培养物中的生长情况。白色念珠菌的生长通常受到需氧菌和厌氧菌高菌数的限制。无论是通过白色念珠菌-cfc-单培养物的连续流入，还是通过将高浓度白色念珠菌悬浮液间歇性输入系统，都无法在粪便菌群中实现其生长。如果系统在有氧条件下运行，可以观察到白色念珠菌有少量菌丝生长的情况。然而，几天后，粪便菌群再次抑制了酵母菌的进一步生长。只有通过抗生素对需氧和厌氧微生物群落的显著破坏，才会导致白色念珠菌的生长或过度生长。
