Henseler T
Universitäts-Hautklinik, Kiel, BR Deutschland.
Mycoses. 1995;38 Suppl 1:7-13. doi: 10.1111/j.1439-0507.1995.tb00478.x.
We investigated skin diseases associated with mucocutaneous Candida infection by analyzing the clinical records of 44695 in-patients of the department of dermatology of Kiel. For more than eighty skin diseases the relative risk (RR) was calculated by age-and sex-adjusting methods. 1996 patients demonstrated a mucocutaneous candidosis, 14.8% of them being hospitalized because of extensive Candida infection. In patients with dermatomyositis, bullous pemphigus, tinea inguinalis, and condylomata acuminata a Candida infection was observed more than threefold than expected. Furthermore, patients with urticaria, folliculitis, and bullous pemphigoid demonstrated candidosis more than twice as often as control patients. In addition, patients with erysipelas, acne, psoriasis, and atopic dermatitis showed a candidosis significantly more often (RR between 1.3 and 1.6). Some internistic maladies were investigated, too. In patients presenting with diabetes mellitus, heart-insufficiency, hypertension, chronic tonsillitis, and urinary tract infection a mucocutaneous Candida infection was significantly increased.
我们通过分析基尔皮肤科44695名住院患者的临床记录，研究了与皮肤黏膜念珠菌感染相关的皮肤病。对于八十多种皮肤病，采用年龄和性别调整方法计算相对风险（RR）。1996名患者患有皮肤黏膜念珠菌病，其中14.8%因广泛念珠菌感染住院。在皮肌炎、大疱性天疱疮、腹股沟癣和尖锐湿疣患者中，观察到念珠菌感染比预期多三倍以上。此外，荨麻疹、毛囊炎和大疱性类天疱疮患者的念珠菌病发生率是对照患者的两倍多。此外，丹毒、痤疮、银屑病和特应性皮炎患者的念珠菌病发生率明显更高（RR在1.3至1.6之间）。还对一些内科疾病进行了调查。患有糖尿病、心力衰竭、高血压、慢性扁桃体炎和尿路感染的患者，皮肤黏膜念珠菌感染明显增加。
