Trampert L, Holle L H, Berberich R, Alexander C, Ukena D, Ruth T, Sybrecht G W, Oberhausen E
Abteilung für Nuklearmedizin, Universitätskliniken Homburg/Saar, FRG.
Nuklearmedizin. 1995 Jun;34(3):79-86.
The diagnosis of primary lung tumors requires a precise staging according to the TNM classification. In contrast to established imaging methods 18FDG describes the functional metabolic processes in the tumor tissue due to increased glycolysis. This paper describes the use of 18FDG in the primary staging of lung tumors and metastases. 44 patients were studied with a gamma camera and a 511 keV collimator. In comparison to pulmonary tumors and metastases detected by other imaging methods (107) the accumulation of 18FDG has a sensitivity of 85%, in lesions verified by histology (50) of 89%, in primary tumors (35) of 100% and in metastases (63) of 76%. As an alternative to FDG PET studies, primary staging of lung tumors is possible with a gamma camera, suitable for ECT and fitted with a 511 keV collimator.
原发性肺肿瘤的诊断需要根据TNM分类进行精确分期。与已有的成像方法不同，18FDG由于糖酵解增加而描述肿瘤组织中的功能代谢过程。本文描述了18FDG在肺肿瘤和转移瘤的初始分期中的应用。对44例患者使用γ相机和511keV准直器进行了研究。与通过其他成像方法检测到的肺肿瘤和转移瘤（107例）相比，18FDG的积聚在敏感性方面，在这些病变中为85%，在经组织学证实的病变（50例）中为89%，在原发性肿瘤（35例）中为100%，在转移瘤（63例）中为76%。作为FDG PET研究的替代方法，使用适合ECT且配备511keV准直器的γ相机对肺肿瘤进行初始分期是可行的。
