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[乳腺癌延迟诊断与治疗对预后的意义]

[Significance for prognosis of delayed diagnosis and treatment of breast cancer].

作者信息

Afzelius P, Zedeler K, Sommer H, Mouridsen H T, Blichert-Toft M

机构信息

Danish Breast Cancer Cooperative Group's (DBCG) sekretariat, Rigshospitalet, København.

出版信息

Ugeskr Laeger. 1995 Jun 26;157(26):3762-5.

PMID:7631453
Abstract

In a study of 7608 patients with primary breast cancer the effect of patient's and doctor's delay on survival was examined. The delay was arbitrarily divided into the following intervals: Short (0-14 days), intermediate (15-60 days) and long (> 60 days). The delay had significant influence on survival. A long patient's delay was associated with an unfavourable outcome, as compared with a short delay. On the contrary, the prognosis was better for patients with a long doctor's delay compared to that of a short doctor's delay. Overall, when corrected for age, the prognostic value of delay in terms of mortality increased by 24% for a long patient's delay compared to a short one, and by 13% for a short doctor's delay compared to a long one. This suggests that all causes of delay should be kept at a minimum.

摘要

在一项针对7608例原发性乳腺癌患者的研究中,研究了患者及医生的延误对生存的影响。延误被任意划分为以下时间段:短(0 - 14天)、中(15 - 60天)和长(> 60天)。延误对生存有显著影响。与短延误相比,患者的长延误与不良结局相关。相反,与医生短延误的患者相比,医生长延误的患者预后更好。总体而言,校正年龄后,与短患者延误相比,长患者延误在死亡率方面的预后价值增加了24%,与长医生延误相比,短医生延误的预后价值增加了13%。这表明应将所有延误原因降至最低。

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