Abdel-Wareth L O, Lirenman D S, Halstead A C, McLellan D, Carleton B C
Department of Pathology, University of British Columbia, Vancouver, Canada.
Pediatr Nephrol. 1995 Jun;9(3):348-50. doi: 10.1007/BF02254207.
We report a case of spurious hyperchloraemia, elevated total carbon dioxide and negative anion gap 9 days following a voiding cystourethrogram (VCU) in a patient with bladder exstrophy and obstructive uropathy. We believe that the spurious laboratory results were due to analytical interference of the absorbed iodine with the method of bicarbonate and chloride measurement. The absorbed iodine was retained in the circulation for an extended period because of associated renal impairment. Our patient was also on piperacillin which might have interfered with iodine clearance. Physicians and laboratory pathologists should be aware of this effect when interpreting laboratory results of patients who have undergone a VCU in association with obstructive uropathy and impaired renal function.
我们报告一例膀胱外翻和梗阻性尿路病患者在排尿性膀胱尿道造影（VCU）后9天出现假性高氯血症、总二氧化碳升高和阴离子间隙为负的病例。我们认为，这些假性实验室结果是由于吸收的碘对碳酸氢盐和氯离子测量方法产生分析干扰所致。由于合并肾功能损害，吸收的碘在循环中保留了较长时间。我们的患者还使用了哌拉西林，这可能干扰了碘的清除。在解读患有梗阻性尿路病和肾功能受损且接受过VCU的患者的实验室结果时，医生和实验室病理学家应意识到这种影响。
