O'Carroll R E
MRC Brain Metabolism Unit, Royal Edinburgh Hospital, Scotland, UK.
Schizophr Res. 1995 May;15(3):299-301. doi: 10.1016/0920-9964(94)00052-a.
Eight acutely ill deluded schizophrenic patients were compared with eight matched recovered patients on an associative learning task. Ten word pair associations were presented over five trials. Subsequently the subjects were presented with ten novel pairings over three trials, one word from the first pair associated with a new partner. Recovered patients performed better than acutely ill patients on both stages of the task. This result does not support the neuropsychological model of Gray et al. (1991) which predicts that acute schizophrenia is characterised by a weakening of the effect of previous experience on new learning.
在一项联想学习任务中,对八名急性发病的妄想型精神分裂症患者与八名匹配的康复患者进行了比较。在五次试验中呈现了十对单词联想。随后,在三次试验中向受试者呈现十对新的配对,第一对中的一个单词与一个新的配对词相关联。在任务的两个阶段,康复患者的表现均优于急性发病患者。这一结果不支持格雷等人(1991年)的神经心理学模型,该模型预测急性精神分裂症的特征是先前经验对新学习的影响减弱。