Pu Y M, Wang J J, Wang T, Yu Q X
Department of Biological Science and Technology, Najing University, P.R. China.
Neuroreport. 1995 May 9;6(7):985-8. doi: 10.1097/00001756-199505090-00009.
Effects of stimulating the cerebellar interpositus nucleus (IN) on the neuronal activity of lateral hypothalamic area (LHA) were first observed in the cat. The results showed that (1) IN stimulation could elicit inhibitory, excitatory, inhibitory-excitatory and excitatory-inhibitory responses from LHA neurones, with a majority of inhibitory responses (46.9%); (2) the responsive latencies of LHA neurones to IN stimulation ranged from 5 to 45 ms, while most (83.6%) showed a short latency of < 15 ms; (3) of 67 LHA neurones which responded to the IN stimulation, 42 (62.7%) cells were identified to be glucose-sensitive neurones. These results suggest that IN may be involved in the role of LHA modulating food intake behaviour, as well as other non-somatic functions.
在猫身上首次观察到刺激小脑间位核（IN）对下丘脑外侧区（LHA）神经元活动的影响。结果表明：（1）刺激IN可引起LHA神经元产生抑制、兴奋、抑制-兴奋和兴奋-抑制反应，其中大多数为抑制反应（46.9%）；（2）LHA神经元对IN刺激的反应潜伏期为5至45毫秒，而大多数（83.6%）表现出小于15毫秒的短潜伏期；（3）在67个对IN刺激有反应的LHA神经元中，42个（62.7%）细胞被确定为葡萄糖敏感神经元。这些结果表明，IN可能参与LHA调节食物摄入行为的作用，以及其他非躯体功能。
