Wang T, Chen W Y, Chen J, Yu Q X, Wang J J
Department of Biology, Nanjing University.
Sheng Li Xue Bao. 1993 Aug;45(4):338-47.
In pentobarbital anaesthetized cat, stimulating lateral hypothalamic area (LHA) and ventromedial nucleus (VMN) of the hypothalamus could elicit inhibitory, excitatory or inhibitory-excitatory responses of cerebellar Purkinje cells (PC) and non-Purkinje cells (NPC) in the loubles VI and VII. The majority of responses are inhibitory (80.4%) usually with a latency of 10-20 ms, or occassionaly as long as 90 ms. Usually stimulation of LHA was more effective and NPC was more responsive. The aforementioned inhibitory response could be blocked by iv. chlorpheniramine. The possible role of the hypothalamo-cerebellar activity was discussed.
在戊巴比妥麻醉的猫中,刺激下丘脑外侧区(LHA)和下丘脑腹内侧核(VMN)可引发小脑第六和第七小叶浦肯野细胞(PC)和非浦肯野细胞(NPC)的抑制性、兴奋性或抑制 - 兴奋性反应。大多数反应是抑制性的(80.4%),潜伏期通常为10 - 20毫秒,偶尔长达90毫秒。通常刺激LHA更有效,NPC反应更敏感。上述抑制性反应可被静脉注射氯苯那敏阻断。文中讨论了下丘脑 - 小脑活动的可能作用。