Sugino K, Kure Y, Iwasaki H, Ozaki O, Mimura T, Matsumoto A, Ito K
Ito Hospital, Tokyo, Japan.
Surg Today. 1995;25(4):324-8. doi: 10.1007/BF00311254.
To investigate the biological characteristics of papillary thyroid carcinoma from the perspectives of lymph node metastasis, lymph node recurrence, and distant metastasis, 746 patients with nonadvanced papillary thyroid carcinoma were retrospectively studied. There were 76 men and 670 women with a mean age of 42.7 years. The rate of lymph node metastasis was significantly higher in young patients (aged less than 30 years). Lymph node recurrence was observed in 80 patients and distant metastasis in 13, being seen with significant frequency in the young and elderly (aged over 50 years) patients and in the men. The frequency of distant metastasis was significantly greater in the elderly patients and in those with lymph node recurrence. These findings indicate that the role of regional lymph nodes and the clinical meaning of lymph node recurrence differ between young and elderly patients.
为从淋巴结转移、淋巴结复发及远处转移角度研究甲状腺乳头状癌的生物学特性，对746例非晚期甲状腺乳头状癌患者进行回顾性研究。其中男性76例，女性670例，平均年龄42.7岁。年轻患者（年龄小于30岁）的淋巴结转移率显著更高。80例患者出现淋巴结复发，13例出现远处转移，在年轻及老年（年龄超过50岁）患者和男性中出现的频率显著。老年患者及有淋巴结复发的患者中远处转移的频率显著更高。这些发现表明，年轻和老年患者区域淋巴结的作用及淋巴结复发的临床意义有所不同。
