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采用切除及搭桥术治疗一名有川崎病病史的成年患者的巨大冠状动脉瘤:病例报告

Treatment of a giant coronary artery aneurysm in an adult with a history of Kawasaki disease by resection and bypass grafting: report of a case.

作者信息

Okumori M, Tokuno S, Nogami Y, Kann I, Tanaka Y

机构信息

Department of Thoracic Surgery, Japan Self-Defense Forces Central Hospital, Tokyo.

出版信息

Surg Today. 1995;25(4):373-7. doi: 10.1007/BF00311264.

Abstract

We report herein the case of a 22-year-old man with a history of Kawasaki disease who developed a giant calcified aneurysm of the left main coronary artery. The aneurysm was successfully resected and coronary bypass surgery was performed using the bilateral internal thoracic arteries. The resected aneurysm, the maximal diameter of which was 27 mm, showed heavy calcification of the inner layer and extended into the adjacent coronary arteries, producing a significant narrowing of the lumen of both the left main trunk (50%) and the anterior descending branch (50%). Extensive intimal calcification presumably prevented normal luminal development and produced a significant narrowing as the patient grew into adulthood. A cause for stenotic lesions developing in the coronary artery adjacent to a coronary aneurysm in adults with a history of Kawasaki disease is suggested here by the resected aneurysm seen in this patient. Thus, adult patients with giant coronary artery aneurysms and significant stenotic lesions of the coronary artery associated with Kawasaki disease may require aneurysmectomy in addition to bypass surgery.

摘要

我们在此报告一例22岁男性患者,其有川崎病病史,发生了左冠状动脉主干巨大钙化动脉瘤。该动脉瘤成功切除,并使用双侧胸廓内动脉进行了冠状动脉搭桥手术。切除的动脉瘤最大直径为27 mm,显示内层重度钙化并延伸至相邻冠状动脉,导致左主干管腔(50%)和前降支管腔(50%)明显狭窄。广泛的内膜钙化可能阻碍了正常管腔发育,并随着患者成年而导致明显狭窄。通过该患者切除的动脉瘤,提示了有川崎病病史的成年患者冠状动脉瘤邻近冠状动脉出现狭窄病变的原因。因此,患有巨大冠状动脉瘤且伴有与川崎病相关的明显冠状动脉狭窄病变的成年患者,除搭桥手术外可能还需要进行动脉瘤切除术。

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