Bøhler E, Singey J, Bergström S
Department of Paediatrics, Ullevål Hospital, Norway.
Acta Paediatr. 1995 May;84(5):478-83. doi: 10.1111/j.1651-2227.1995.tb13678.x.
In a rural area of Bhutan, anthropometric measurements of 113 children and interviews with their mothers were carried out monthly for 32 months. The purpose of the study was to investigate the effect of a mother's subsequent pregnancy on growth in weight of her last-born child. The children whose mothers had a subsequent birth interval of 18-30 months were matched for date of birth with children whose mothers did not become pregnant. Growth of the children during the subsequent pregnancy was compared with growth during the same period of children whose mothers were not pregnant. A statistically significant reduction of 28% was found (p < 0.05), which was most pronounced in early pregnancy. A similar trend was found for change in mid-upper-arm circumference (p < 0.05). The study provides evidence of a causal relationship between a moderate subsequent pregnancy interval and a concurrent reduction in growth rate for the previous child.
在不丹的一个农村地区，对113名儿童进行了为期32个月的每月人体测量，并对他们的母亲进行了访谈。该研究的目的是调查母亲随后怀孕对其最小孩子体重增长的影响。将母亲随后生育间隔为18至30个月的孩子与母亲未怀孕的孩子按出生日期进行匹配。将随后怀孕的孩子的生长情况与母亲未怀孕的孩子在同一时期的生长情况进行比较。结果发现有统计学意义的28%的下降（p < 0.05），这在怀孕早期最为明显。在上臂中部周长变化方面也发现了类似趋势（p < 0.05）。该研究提供了证据，证明适度的随后怀孕间隔与前一个孩子生长速率同时降低之间存在因果关系。
