Mansour R T, Aboulghar M A, Serour G I
Egyptian IVF-ET Center, Maadi, Cairo.
J Assist Reprod Genet. 1994 Oct;11(9):478-81. doi: 10.1007/BF02215712.
To study the optimum time for ovum pickup after human chorionic gonadotropin (hCG) injection in in vitro fertilization.
Prospective randomized study.
The Egyptian IVF-ET center.
Ninety couples with male factor infertility enrolled for intracytoplasmic sperm injection, divided into three groups. Ovum pickup was performed at 35 hr (group A), 36 hr (group B), and 37 hr (group C) after hCG injection.
Number of metaphase II oocytes was significantly higher in group B compared to group A. There was no significant difference between group B and C. Fertilization rate was equal in all groups. The number of fertilized oocytes was significantly higher in group B as compared to group A, and there was no significant difference between groups B and C.
Oocyte maturity in gonadotropin releasing hormone analogue agonist/human menopausal gonadotropin stimulated cycles is attained 36 hr after hCG injection. Oocyte retrieval should not be performed before 36 hr, and there is no risk of spontaneous ovulation between 36 and 37 hr.
研究体外受精中注射人绒毛膜促性腺激素(hCG)后取卵的最佳时间。
前瞻性随机研究。
埃及体外受精-胚胎移植中心。
90对因男性因素不孕而行卵胞浆内单精子注射的夫妇,分为三组。分别在注射hCG后35小时(A组)、36小时(B组)和37小时(C组)进行取卵。
B组中期II期卵母细胞数量显著高于A组。B组和C组之间无显著差异。所有组的受精率相同。B组受精的卵母细胞数量显著高于A组,B组和C组之间无显著差异。
在促性腺激素释放激素类似物激动剂/人绝经期促性腺激素刺激周期中,hCG注射后36小时达到卵母细胞成熟。取卵不应在36小时之前进行,在36至37小时之间无自发排卵风险。