• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

体外受精中人类绒毛膜促性腺激素-取卵间隔最佳时间的研究。

Study of the optimum time for human chorionic gonadotropin-ovum pickup interval in in vitro fertilization.

作者信息

Mansour R T, Aboulghar M A, Serour G I

机构信息

Egyptian IVF-ET Center, Maadi, Cairo.

出版信息

J Assist Reprod Genet. 1994 Oct;11(9):478-81. doi: 10.1007/BF02215712.

DOI:10.1007/BF02215712
PMID:7633170
Abstract

OBJECTIVE

To study the optimum time for ovum pickup after human chorionic gonadotropin (hCG) injection in in vitro fertilization.

DESIGN

Prospective randomized study.

SETTING

The Egyptian IVF-ET center.

PATIENTS

Ninety couples with male factor infertility enrolled for intracytoplasmic sperm injection, divided into three groups. Ovum pickup was performed at 35 hr (group A), 36 hr (group B), and 37 hr (group C) after hCG injection.

RESULTS

Number of metaphase II oocytes was significantly higher in group B compared to group A. There was no significant difference between group B and C. Fertilization rate was equal in all groups. The number of fertilized oocytes was significantly higher in group B as compared to group A, and there was no significant difference between groups B and C.

CONCLUSION

Oocyte maturity in gonadotropin releasing hormone analogue agonist/human menopausal gonadotropin stimulated cycles is attained 36 hr after hCG injection. Oocyte retrieval should not be performed before 36 hr, and there is no risk of spontaneous ovulation between 36 and 37 hr.

摘要

目的

研究体外受精中注射人绒毛膜促性腺激素(hCG)后取卵的最佳时间。

设计

前瞻性随机研究。

地点

埃及体外受精-胚胎移植中心。

患者

90对因男性因素不孕而行卵胞浆内单精子注射的夫妇,分为三组。分别在注射hCG后35小时(A组)、36小时(B组)和37小时(C组)进行取卵。

结果

B组中期II期卵母细胞数量显著高于A组。B组和C组之间无显著差异。所有组的受精率相同。B组受精的卵母细胞数量显著高于A组,B组和C组之间无显著差异。

结论

在促性腺激素释放激素类似物激动剂/人绝经期促性腺激素刺激周期中,hCG注射后36小时达到卵母细胞成熟。取卵不应在36小时之前进行,在36至37小时之间无自发排卵风险。

相似文献

1
Study of the optimum time for human chorionic gonadotropin-ovum pickup interval in in vitro fertilization.体外受精中人类绒毛膜促性腺激素-取卵间隔最佳时间的研究。
J Assist Reprod Genet. 1994 Oct;11(9):478-81. doi: 10.1007/BF02215712.
2
Weekend-free scheduled IVF/ICSI procedures and single embryo transfer do not reduce live-birth rates in a general infertile population.无周末安排的体外受精/卵胞浆内单精子注射程序及单胚胎移植并不会降低普通不孕人群的活产率。
Acta Obstet Gynecol Scand. 2017 Dec;96(12):1423-1429. doi: 10.1111/aogs.13235. Epub 2017 Oct 31.
3
In vivo maturation of oocytes by extending the interval between human chorionic gonadotropin administration and oocyte retrieval.通过延长人绒毛膜促性腺激素给药与卵母细胞采集之间的间隔时间实现卵母细胞的体内成熟。
Fertil Steril. 2006 Sep;86(3):583-7. doi: 10.1016/j.fertnstert.2006.02.091. Epub 2006 Jul 7.
4
Maturity and fertility of rhesus monkey oocytes collected at different intervals after an ovulatory stimulus (human chorionic gonadotropin) in in vitro fertilization cycles.在体外受精周期中,对排卵刺激(人绒毛膜促性腺激素)后不同时间采集的恒河猴卵母细胞的成熟度和受精能力进行研究。
Mol Reprod Dev. 1996 Jan;43(1):76-81. doi: 10.1002/(SICI)1098-2795(199601)43:1<76::AID-MRD10>3.0.CO;2-2.
5
Superovulation of mice with human menopausal gonadotropin or pure follicle-stimulating hormone in combination with human chorionic gonadotropin and the effects of oocyte aging on in vitro fertilization.
J In Vitro Fert Embryo Transf. 1986 Oct;3(5):314-8. doi: 10.1007/BF01133392.
6
Dual trigger with gonadotropin-releasing hormone agonist and standard dose human chorionic gonadotropin to improve oocyte maturity rates.使用促性腺激素释放激素激动剂和标准剂量人绒毛膜促性腺激素的双重触发以提高卵母细胞成熟率。
Fertil Steril. 2014 Aug;102(2):405-9. doi: 10.1016/j.fertnstert.2014.04.028. Epub 2014 May 17.
7
Dual trigger with gonadotropin-releasing hormone agonist and recombinant human chorionic gonadotropin improves in vitro fertilization outcome in gonadotropin-releasing hormone antagonist cycles.促性腺激素释放激素激动剂与重组人绒毛膜促性腺激素双重触发可改善促性腺激素释放激素拮抗剂周期的体外受精结局。
J Obstet Gynaecol Res. 2016 Sep;42(9):1146-51. doi: 10.1111/jog.13021. Epub 2016 May 15.
8
Ultrasound control of clomiphene/human chorionic gonadotropin stimulated cycles for oocyte recovery and in vitro fertilization.
Fertil Steril. 1981 Sep;36(3):316-9. doi: 10.1016/s0015-0282(16)45731-6.
9
The effects of low-dose human chorionic gonadotropin combined with human menopausal gonadotropin protocol on women with hypogonadotropic hypogonadism undergoing ovarian stimulation for in vitro fertilization.低剂量人绒毛膜促性腺激素联合人绝经期促性腺激素方案对接受体外受精卵巢刺激的低促性腺激素性性腺功能减退症妇女的影响。
Clin Endocrinol (Oxf). 2018 Jan;88(1):77-87. doi: 10.1111/cen.13481. Epub 2017 Oct 16.
10
Luteinizing response to human chorionic gonadotropin does not predict outcome in gonadotropin releasing hormone agonist-suppressed/human menopausal gonadotropin-stimulated in vitro fertilization (IVF) cycles.对人绒毛膜促性腺激素的促黄体生成素反应不能预测促性腺激素释放激素激动剂抑制/人绝经后促性腺激素刺激的体外受精(IVF)周期的结局。
J Assist Reprod Genet. 1992 Jun;9(3):244-7. doi: 10.1007/BF01203821.

引用本文的文献

1
A valuable predictive model for optimizing the timing of oocyte retrieval: a retrospective analysis of oocyte retrieval time in 49,961 oocyte pickup (OPU) cycles.一种用于优化取卵时机的有价值的预测模型:对49961个取卵周期中取卵时间的回顾性分析。
Reprod Biol Endocrinol. 2025 Jul 23;23(1):107. doi: 10.1186/s12958-025-01441-9.
2
Is there a preferred time interval between gonadotropin-releasing hormone (GnRH) agonist trigger and oocyte retrieval in GnRH antagonist cycles? A retrospective cohort of planned fertility preservation cycles.促性腺激素释放激素(GnRH)激动剂扳机与 GnRH 拮抗剂周期中卵母细胞回收之间是否存在首选的时间间隔?一项计划进行生育力保存周期的回顾性队列研究。
J Assist Reprod Genet. 2024 Jun;41(6):1531-1538. doi: 10.1007/s10815-024-03083-z. Epub 2024 Mar 16.
3

本文引用的文献

1
Timing of ovulation by LH assay.通过促黄体生成素检测来确定排卵时间。
Fertil Steril. 1959 May-Jun;10(3):212-26. doi: 10.1016/s0015-0282(16)33421-5.
2
In vitro maturation and the fertilization and developmental competence of oocytes recovered from untreated polycystic ovarian patients.未治疗的多囊卵巢患者回收卵母细胞的体外成熟、受精及发育能力
Fertil Steril. 1994 Aug;62(2):353-62. doi: 10.1016/s0015-0282(16)56891-5.
3
Minimum time lapse between luteinizing hormone surge or human chorionic gonadotropin administration and follicular rupture.
Time interval between hCG administration and oocyte retrieval and ART outcomes: an updated systematic review and meta-analysis.人绒毛膜促性腺激素注射时间与卵母细胞获取时间间隔和辅助生殖技术结局:一项更新的系统评价和荟萃分析。
Reprod Biol Endocrinol. 2023 Jul 3;21(1):61. doi: 10.1186/s12958-023-01110-9.
4
The ovulation trigger-OPU time interval of different ovarian protocols in ART: a retrospective study.ART 中不同卵巢刺激方案的排卵触发-OPU 时间间隔:一项回顾性研究。
Arch Gynecol Obstet. 2020 Aug;302(2):519-527. doi: 10.1007/s00404-020-05568-5. Epub 2020 Jun 3.
5
Optimal Ovulation Trigger-Oocyte Pickup Interval in Progestin-Primed Ovarian Stimulation Protocol: A Retrospective Study Using Propensity Score Matching.孕激素预处理卵巢刺激方案中最佳排卵触发-卵母细胞采集间隔:一项使用倾向评分匹配的回顾性研究
Front Endocrinol (Lausanne). 2019 Oct 15;10:694. doi: 10.3389/fendo.2019.00694. eCollection 2019.
6
Novel Concepts for Inducing Final Oocyte Maturation in In Vitro Fertilization Treatment.在体外受精治疗中诱导卵母细胞最终成熟的新概念。
Endocr Rev. 2018 Oct 1;39(5):593-628. doi: 10.1210/er.2017-00236.
7
Post-ovulatory aging of oocytes disrupts kinase signaling pathways and lysosome biogenesis.排卵后卵母细胞的老化会破坏激酶信号通路和溶酶体生物发生。
Mol Reprod Dev. 2014 Oct;81(10):928-45. doi: 10.1002/mrd.22413. Epub 2014 Sep 19.
8
The effectiveness of earlier oocyte retrieval in the case of a premature luteinizing hormone surge on hCG day in in vitro fertilization-embryo transfer cycles.在体外受精-胚胎移植周期中,hCG日出现过早的促黄体生成素峰时提前取卵的有效性。
Clin Exp Reprod Med. 2013 Jun;40(2):90-4. doi: 10.5653/cerm.2013.40.2.90. Epub 2013 Jun 30.
9
A Live Birth Subsequent to IVF following Egg Retrieval Only 12 Hours after hCG Priming.仅在注射人绒毛膜促性腺激素(hCG)启动后12小时取卵的体外受精(IVF)后活产。
Case Rep Obstet Gynecol. 2013;2013:634385. doi: 10.1155/2013/634385. Epub 2013 May 16.
10
The time interval between hCG priming and oocyte retrieval in ART program: a meta-analysis.ART 方案中 hCG 预刺激与卵母细胞采集的时间间隔:一项荟萃分析。
J Assist Reprod Genet. 2011 Sep;28(10):901-10. doi: 10.1007/s10815-011-9613-x. Epub 2011 Jul 27.
促黄体生成素激增或注射人绒毛膜促性腺激素与卵泡破裂之间的最短时间间隔。
Fertil Steril. 1982 Jan;37(1):50-3. doi: 10.1016/s0015-0282(16)45976-5.
4
Temporal relationships between ovulation and defined changes in the concentration of plasma estradiol-17 beta, luteinizing hormone, follicle-stimulating hormone, and progesterone. I. Probit analysis. World Health Organization, Task Force on Methods for the Determination of the Fertile Period, Special Programme of Research, Development and Research Training in Human Reproduction.排卵与血浆雌二醇-17β、促黄体生成素、促卵泡生成素和孕酮浓度特定变化之间的时间关系。I. 概率分析。世界卫生组织,人类生殖研究、发展与研究培训特别规划确定排卵期方法特别工作组。
Am J Obstet Gynecol. 1980 Oct 15;138(4):383-90.
5
Ovulation timing by luteinizing hormone assay and follicle puncture.通过促黄体生成素检测和卵泡穿刺确定排卵时间。
Obstet Gynecol. 1983 Aug;62(2):191-5.
6
Control of human ovulation, fertilization and implantation.人类排卵、受精和着床的控制。
Proc R Soc Med. 1974 Sep;67(9):932-6. doi: 10.1177/003591577406700942.
7
Luteinization to oocyte retrieval delay in women in whom multiple follicular growth was induced as part of an in vitro fertilization/gamete intrafallopian transfer program.在作为体外受精/配子输卵管内移植计划一部分而诱导多个卵泡生长的女性中,从黄体化到取卵的延迟。
Fertil Steril. 1990 Apr;53(4):735-7. doi: 10.1016/s0015-0282(16)53474-8.