Hoult I J, de Crespigny L C, O'Herlihy C, Speirs A L, Lopata A, Kellow G, Johnston I, Robinson H P
Fertil Steril. 1981 Sep;36(3):316-9. doi: 10.1016/s0015-0282(16)45731-6.
Three pregnancies have been achieved through in vitro fertilization (IVF) following clomiphene/human chorionic gonadotropin (hCG) stimulation monitored only with ultrasound. When the results of 120 stimulated cycles were compared with those from 213 spontaneous cycles during a one-year period, the clomiphene-ultrasound-hCG method led to a significantly higher laparoscopy rate as well as significantly better yields of mature oocytes and embryos for intrauterine transfer. The luteal phase was normal in the stimulated group. This ultrasound-monitored technique was simpler to manage and less costly and appears to be the current method of choice for obtaining oocytes for IVF.
