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Urea and guanidine hydrochloride denaturation curves.

作者信息

Shirley B A

机构信息

Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, USA.

出版信息

Methods Mol Biol. 1995;40:177-90. doi: 10.1385/0-89603-301-5:177.

DOI:10.1385/0-89603-301-5:177
PMID:7633522
Abstract
摘要

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Urea and guanidine hydrochloride denaturation curves.尿素和盐酸胍变性曲线。
Methods Mol Biol. 1995;40:177-90. doi: 10.1385/0-89603-301-5:177.
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Protein denaturation with guanidine hydrochloride or urea provides a different estimate of stability depending on the contributions of electrostatic interactions.根据静电相互作用的贡献,用盐酸胍或尿素使蛋白质变性可提供不同的稳定性估计。
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