McLellan D L
University Rehabilitation Research Unit, Southampton General Hospital, UK.
Baillieres Clin Neurol. 1995 Apr;4(1):115-29.
Chronic or contingent electrical stimulation at various sites in the region of the ventrolateral nucleus of the thalamus can suppress contralateral intention tremor and the resting tremor seen in Parkinson's disease and idiopathic tremor. The procedure appears to carry less risk, in producing physical or cognitive impairment, than stereotactic ablation. However, the procedure has been tried in few centres to date and long term follow-up studies are needed to place this treatment in its true clinical perspective. It is important to assess patients' needs very carefully to ensure that their functional objectives will be best met by treatments of this kind, and that the requirement for regular monitoring and periodic reassessment can be fully met during long term follow-up.
对丘脑腹外侧核区域的不同部位进行慢性或偶然的电刺激,可以抑制帕金森病和特发性震颤中出现的对侧意向性震颤和静止性震颤。与立体定向消融相比,该手术在导致身体或认知障碍方面的风险似乎更小。然而,迄今为止,很少有中心尝试过该手术,需要进行长期随访研究,以便从真正的临床角度看待这种治疗方法。非常仔细地评估患者的需求很重要,以确保这类治疗能够最好地满足他们的功能目标,并且在长期随访期间能够充分满足定期监测和定期重新评估的要求。