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血管内支架的体外评估,以评估其用于血管内移植物固定的适用性。

In vitro evaluation of endovascular stents to assess suitability for endovascular graft fixation.

作者信息

Andrews S M, Anson A W, Greenhalgh R M, Nott D M

机构信息

Department of Vascular Surgery, Charing Cross Hospital, London, U.K.

出版信息

Eur J Vasc Endovasc Surg. 1995 May;9(4):403-7. doi: 10.1016/s1078-5884(05)80007-3.

Abstract

OBJECTIVE

To compare and ascertain the suitability for endovascular aortic graft fixation of the Palmaz stent, the Strecker stent, the modified Gianturco-Z stent, the Wallstent and a new stent made of the shape memory alloy nitinol. DESIGN, SETTING AND MATERIALS: In vitro studies using a simple tensiometer to assess the forces required to distract each stent from porcine aorta; and using a high-pressure, pulsatile-flow pump to measure flow rates required to dislodge stents holding grafts within porcine aortas, with assessment using endovascular ultrasound.

RESULTS

The Palmaz, the modified Gianturco-Z and the nitinol stents resisted significantly greater distraction forces than the Wallstent, but endovascular ultrasound examination revealed that the modified Gianturco-Z stent was seen to move away from the aortic wall at high flow rates precluding adequate fixation. The Strecker stent could not be assessed using these techniques.

CONCLUSIONS

A nitinol stent may be suitable for aortic graft fixation, has characteristics similar to the Palmaz stent and has shape memory effect which may overcome the difficulties of introduction of wider diameter stents through narrow arteries.

摘要

目的

比较并确定帕尔马兹支架、斯特雷克支架、改良的朱安特科-Z支架、华尔支架以及一种由形状记忆合金镍钛诺制成的新型支架用于血管内主动脉移植物固定的适用性。

设计、地点和材料:采用体外研究,使用简易张力计评估将每个支架从猪主动脉撑开所需的力;使用高压、搏动流泵测量将固定移植物的支架从猪主动脉中移出所需的流速,并通过血管内超声进行评估。

结果

帕尔马兹支架、改良的朱安特科-Z支架和镍钛诺支架比华尔支架抵抗撑开力的能力显著更强,但血管内超声检查显示,改良的朱安特科-Z支架在高流速时会从主动脉壁移开,无法实现充分固定。无法使用这些技术评估斯特雷克支架。

结论

镍钛诺支架可能适用于主动脉移植物固定,具有与帕尔马兹支架相似的特性,并且具有形状记忆效应,这可能克服通过狭窄动脉引入直径更大支架的困难。

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