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Current evidence for and against the TSH receptor being the common antigen in Graves' disease and thyroid associated ophthalmopathy.

作者信息

Paschke R, Vassart G, Ludgate M

机构信息

Service de Génétique Médicale, Université Libre de Bruxelles, Belgique.

出版信息

Clin Endocrinol (Oxf). 1995 Jun;42(6):565-9. doi: 10.1111/j.1365-2265.1995.tb02681.x.

DOI:10.1111/j.1365-2265.1995.tb02681.x
PMID:7634495
Abstract
摘要

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Current evidence for and against the TSH receptor being the common antigen in Graves' disease and thyroid associated ophthalmopathy.支持和反对促甲状腺激素受体作为格雷夫斯病和甲状腺相关眼病共同抗原的现有证据。
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Single nucleotide polymorphism 1623 A/G (rs180195) in the promoter of the Thyroglobulin gene is associated with autoimmune thyroid disease but not with thyroid ophthalmopathy.甲状腺球蛋白基因启动子中的单核苷酸多态性1623 A/G（rs180195）与自身免疫性甲状腺疾病相关，但与甲状腺眼病无关。
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J Hum Genet. 2017 Mar;62(3):373-377. doi: 10.1038/jhg.2016.135. Epub 2016 Nov 10.
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Does autoimmunity against thyroglobulin play a role in the pathogenesis of Graves' ophthalmopathy: a review.
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Disrupted TSH Receptor Expression in Female Mouse Lung Fibroblasts Alters Subcellular IGF-1 Receptor Distribution.雌性小鼠肺成纤维细胞中促甲状腺激素受体表达紊乱会改变胰岛素样生长因子-1受体的亚细胞分布。
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J Endocrinol Invest. 2010 Jun;33(6):414-21. doi: 10.1007/BF03346614.
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J Immunol. 2008 Sep 15;181(6):4397-405. doi: 10.4049/jimmunol.181.6.4397.