Yang Dawn D, Gonzalez Mithra O, Durairaj Vikram D
University of Colorado Denver School of Medicine, Department of Ophthalmology, Division of Oculofacial Plastic and Reconstructive Surgery, United States.
Saudi J Ophthalmol. 2011 Jan;25(1):3-13. doi: 10.1016/j.sjopt.2010.10.001. Epub 2010 Oct 26.
Thyroid eye disease (TED) is the most common cause of orbital disease in adults. The immunologic pathogenesis of TED has been an area of active research and considerable progress has resulted in an expansion of therapeutic options. Although surgical intervention may be required, a majority of TED patients can be managed with medical therapies. Of medical therapies, glucocorticoids remain the agent of choice in the control of TED activity. The objective of this review is to discuss the paradigm and options in medical management of TED.
甲状腺眼病(TED)是成人眼眶疾病最常见的病因。TED的免疫发病机制一直是积极研究的领域,并且取得了相当大的进展,从而扩大了治疗选择。虽然可能需要手术干预,但大多数TED患者可以通过药物治疗来管理。在药物治疗中,糖皮质激素仍然是控制TED活动的首选药物。本综述的目的是讨论TED药物治疗的模式和选择。